Metabolic Syndromes as Important Comorbidities in Patients of Inherited Retinal Degenerations: Experiences from the Nationwide Health Database and a Large Hospital-Based Cohort.
Charlson comorbidity index
inherited retinal degenerations
metabolic syndrome
socioeconomic impacts
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
20 02 2021
20 02 2021
Historique:
received:
15
01
2021
revised:
15
02
2021
accepted:
15
02
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
24
4
2021
Statut:
epublish
Résumé
This study aimed to evaluate the medical and socioeconomic impacts of IRDs using the nationwide health database and a large hospital-based cohort. This retrospective cross-sectional cohort study used data from the nationwide National Health Insurance Research Database (NHIRD). All patients with IRD from January 2012 to December 2016 were selected from the NHIRD and matched with the general population at a ratio of 1:4. All variables, including comorbidities, medications, service utilization, and medical costs, within 1 year from the date of the IRD diagnosis, were analyzed. Disability data were retrieved from the Taiwan Inherited retinal degeneration Project (TIP), a medical center-based database. A total of 4447 and 17,788 subjects from the nationwide database were included in the IRD and control groups, respectively. The Charlson comorbidity index score was higher in the IRD group (0.74:0.52,
Identifiants
pubmed: 33672521
pii: ijerph18042065
doi: 10.3390/ijerph18042065
pmc: PMC7923804
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Eur J Ophthalmol. 2006 Nov-Dec;16(6):865-6
pubmed: 17191195
JAMA Ophthalmol. 2020 Jul 1;138(7):756-763
pubmed: 32407444
Ophthalmology. 2019 Sep;126(9):1273-1285
pubmed: 31443789
JAMA. 1999 Jan 6;281(1):10-1
pubmed: 9892430
Trends Genet. 2009 Apr;25(4):156-65
pubmed: 19303164
Diabetes Care. 2004 Sep;27(9):2222-8
pubmed: 15333488
Optom Vis Sci. 2013 May;90(5):488-93
pubmed: 23563443
Med Care. 2005 Nov;43(11):1130-9
pubmed: 16224307
Ophthalmology. 2015 Nov;122(11):2344-50
pubmed: 26394754
Sci Rep. 2017 Apr 12;7:46453
pubmed: 28401923
Ann Agric Environ Med. 2016 Sep 27;23(4):631-635
pubmed: 28030935
Asia Pac J Public Health. 2014 May;26(3):310-9
pubmed: 22535554
Am J Ophthalmol. 2017 May;177:169-174
pubmed: 28237413
Health Aff (Millwood). 2003 May-Jun;22(3):77-88
pubmed: 12757274
Ophthalmic Genet. 2001 Sep;22(3):133-54
pubmed: 11559856
Ann Saudi Med. 2007 Jan-Feb;27(1):18-24
pubmed: 17277499
J Med Genet. 1992 May;29(5):289-90
pubmed: 1583653
Lancet. 2017 Aug 26;390(10097):849-860
pubmed: 28712537
Ophthalmic Epidemiol. 2021 Dec;28(6):533-539
pubmed: 33615979
BMC Health Serv Res. 2010 May 26;10:136
pubmed: 20500894
Asia Pac J Public Health. 2015 Sep;27(6):631-42
pubmed: 26041834
Acta Ophthalmol. 2015 Mar;93(2):134-40
pubmed: 24953749
N Engl J Med. 2008 May 22;358(21):2231-9
pubmed: 18441371
Arch Ophthalmol. 2012 May;130(5):629-34
pubmed: 22652848
J Bone Metab. 2015 Aug;22(3):99-106
pubmed: 26389084
J AAPOS. 2009 Dec;13(6):587-92
pubmed: 20006823