Ribonuclease J-Mediated mRNA Turnover Modulates Cell Shape, Metabolism and Virulence in

Caenorhabditis elegans Corynebacterium diphtheriae RNase J actinobacterium metabolism ribonuclease siderophore tryptophan biosynthesis virulence

Journal

Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893

Informations de publication

Date de publication:
14 Feb 2021
Historique:
received: 04 01 2021
revised: 08 02 2021
accepted: 09 02 2021
entrez: 6 3 2021
pubmed: 7 3 2021
medline: 7 3 2021
Statut: epublish

Résumé

Controlled RNA degradation is a crucial process in bacterial cell biology for maintaining proper transcriptome homeostasis and adaptation to changing environments. mRNA turnover in many Gram-positive bacteria involves a specialized ribonuclease called RNase J (RnJ). To date, however, nothing is known about this process in the diphtheria-causative pathogen

Identifiants

pubmed: 33672886
pii: microorganisms9020389
doi: 10.3390/microorganisms9020389
pmc: PMC7917786
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI110432
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE025015
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI150045
Pays : United States
Organisme : Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases
ID : AI076406 and AI150045
Organisme : NIAID NIH HHS
ID : R56 AI110432
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE017382
Pays : United States
Organisme : NIDCR NIH HHS
ID : DE025015
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI076406
Pays : United States

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Auteurs

Truc Thanh Luong (TT)

Division of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.
Department of Microbiology & Molecular Genetics, University of Texas Health Science Center, Houston, TX 77030, USA.

Minh Tan Nguyen (MT)

Division of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.
NTT Hi-Tech Institute, Nguyen Tat Thanh University, Ho Chi Minh City 70000, Vietnam.

Yi-Wei Chen (YW)

Division of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.

Chungyu Chang (C)

Division of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.

Ju Huck Lee (JH)

Department of Microbiology & Molecular Genetics, University of Texas Health Science Center, Houston, TX 77030, USA.
Biological Resource Center, Korea Research Institute of Bioscience and Biotechnology, Jeollabuk-do 56212, Korea.

Manuel Wittchen (M)

Center for Biotechnology (CeBiTec), Bielefeld University, 33615 Bielefeld, Germany.

HyLam Ton-That (H)

Department of Chemistry, University of California at Irvine, Irvine, CA 92617, USA.

Melissa Cruz (M)

Department of Microbiology & Molecular Genetics, University of Texas Health Science Center, Houston, TX 77030, USA.

Danielle A Garsin (DA)

Department of Microbiology & Molecular Genetics, University of Texas Health Science Center, Houston, TX 77030, USA.

Asis Das (A)

Neag Comprehensive Cancer Center, Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.

Andreas Tauch (A)

Center for Biotechnology (CeBiTec), Bielefeld University, 33615 Bielefeld, Germany.

Hung Ton-That (H)

Division of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.
Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA.

Classifications MeSH