Enterovirus A71 Vaccines.

Enterovirus A71 Sinovac foot and mouth disease (HFMD) hand vaccine

Journal

Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355

Informations de publication

Date de publication:
27 Feb 2021
Historique:
received: 01 02 2021
revised: 22 02 2021
accepted: 22 02 2021
entrez: 6 3 2021
pubmed: 7 3 2021
medline: 7 3 2021
Statut: epublish

Résumé

Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.

Identifiants

pubmed: 33673595
pii: vaccines9030199
doi: 10.3390/vaccines9030199
pmc: PMC7997495
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Subventions

Organisme : NIH HHS
ID : R01 GM126833 to GB and BST
Pays : United States
Organisme : The Ministry of Education in Taiwan and the Ministry of Science and Technology, Taiwan
ID : MOST 108-3017-F-182-001 to SRS

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Auteurs

Mei-Ling Li (ML)

Department of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.

Shin-Ru Shih (SR)

Research Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Department of Laboratory Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Research Center for Chinese Herbal Medicine, Research Center for Food and Cosmetic Safety, and Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan.

Blanton S Tolbert (BS)

Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA.

Gary Brewer (G)

Department of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.

Classifications MeSH