Primordial GATA6 macrophages function as extravascular platelets in sterile injury.
Animals
Ascitic Fluid
/ immunology
Blood Platelets
/ immunology
Cell Aggregation
/ immunology
GATA6 Transcription Factor
/ analysis
Macrophages, Peritoneal
/ chemistry
Mice
Mice, Inbred C57BL
Peritoneum
/ immunology
Scavenger Receptors, Class B
/ immunology
Thrombosis
/ immunology
Tissue Adhesions
/ immunology
Wounds and Injuries
/ immunology
Journal
Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511
Informations de publication
Date de publication:
05 03 2021
05 03 2021
Historique:
received:
29
07
2020
accepted:
08
01
2021
entrez:
6
3
2021
pubmed:
7
3
2021
medline:
1
4
2021
Statut:
ppublish
Résumé
Most multicellular organisms have a major body cavity that harbors immune cells. In primordial species such as purple sea urchins, these cells perform phagocytic functions but are also crucial in repairing injuries. In mammals, the peritoneal cavity contains large numbers of resident GATA6
Identifiants
pubmed: 33674464
pii: 371/6533/eabe0595
doi: 10.1126/science.abe0595
pii:
doi:
Substances chimiques
GATA6 Transcription Factor
0
GATA6 protein, human
0
Scavenger Receptors, Class B
0
Banques de données
Dryad
['10.5061/dryad.05qfttf1w']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.