Efficacy of milbemycin oxime/afoxolaner chewable tablets (NEXGARD SPECTRA
Administration, Oral
Animals
Anthelmintics
/ administration & dosage
Capillaria
/ classification
Dog Diseases
/ drug therapy
Dogs
Enoplida Infections
/ drug therapy
Isoxazoles
/ administration & dosage
Macrolides
/ administration & dosage
Naphthalenes
/ administration & dosage
Tablets
/ administration & dosage
Capillaria aerophila
Capillaria boehmi
Dog
Milbemycin oxime
NEXGARD SPECTRA®
Journal
Parasites & vectors
ISSN: 1756-3305
Titre abrégé: Parasit Vectors
Pays: England
ID NLM: 101462774
Informations de publication
Date de publication:
06 Mar 2021
06 Mar 2021
Historique:
received:
06
12
2020
accepted:
16
02
2021
entrez:
7
3
2021
pubmed:
8
3
2021
medline:
4
9
2021
Statut:
epublish
Résumé
Capillaria aerophila and Capillaria boehmi parasitize the respiratory system of wild and domestic carnivores. Capillaria aerophila inhabits the trachea and bronchi of dogs and cats, while C. boehmi affects the nasal cavities and sinuses of dogs. In dogs the infection may be subclinical or characterized by varying respiratory distress. The present study evaluated the efficacy of an oral formulation containing milbemycin oxime and afoxolaner (NEXGARD SPECTRA Percentage reduction of fecal Capillaria egg counts in the NEXGARD SPECTRA Results of the present study showed that NEXGARD SPECTRA® was safe and highly efficacious in the reduction of C. aerophila and C. boehmi eggs after one treatment with a complete reduction of the egg output after the second administration associated with a recovery from respiratory signs.
Sections du résumé
BACKGROUND
BACKGROUND
Capillaria aerophila and Capillaria boehmi parasitize the respiratory system of wild and domestic carnivores. Capillaria aerophila inhabits the trachea and bronchi of dogs and cats, while C. boehmi affects the nasal cavities and sinuses of dogs. In dogs the infection may be subclinical or characterized by varying respiratory distress.
METHODS
METHODS
The present study evaluated the efficacy of an oral formulation containing milbemycin oxime and afoxolaner (NEXGARD SPECTRA
RESULTS
RESULTS
Percentage reduction of fecal Capillaria egg counts in the NEXGARD SPECTRA
CONCLUSIONS
CONCLUSIONS
Results of the present study showed that NEXGARD SPECTRA® was safe and highly efficacious in the reduction of C. aerophila and C. boehmi eggs after one treatment with a complete reduction of the egg output after the second administration associated with a recovery from respiratory signs.
Identifiants
pubmed: 33676579
doi: 10.1186/s13071-021-04648-y
pii: 10.1186/s13071-021-04648-y
pmc: PMC7937313
doi:
Substances chimiques
Anthelmintics
0
Isoxazoles
0
Macrolides
0
Naphthalenes
0
Tablets
0
afoxolaner
02L07H6D0U
milbemycin oxime
0502PUN0GT
Types de publication
Clinical Trial, Veterinary
Journal Article
Multicenter Study
Randomized Controlled Trial, Veterinary
Langues
eng
Sous-ensembles de citation
IM
Pagination
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