Pyrethroid exposure among children residing in green versus non-green multi-family, low-income housing.
Children
Green housing
Pyrethroids
Urban
Urinary metabolites
Journal
Journal of exposure science & environmental epidemiology
ISSN: 1559-064X
Titre abrégé: J Expo Sci Environ Epidemiol
Pays: United States
ID NLM: 101262796
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
31
07
2020
accepted:
12
02
2021
revised:
03
02
2021
pubmed:
8
3
2021
medline:
3
7
2021
entrez:
7
3
2021
Statut:
ppublish
Résumé
There is growing concern about children's chronic low-level pesticide exposure and its impact on health. Green building practices (e.g., reducing leakage of the thermal and pressure barrier that surrounds the structure, integrated pest management, improved ventilation) have the potential to reduce pesticide exposure. However, the potential impact of living in green housing on children's pesticide exposure is unknown. To address this question, a longitudinal study of pyrethroid metabolites (3-phenoxybenzoic acid [3-PBA], 4-fluoro-3-phenoxybenzoic acid [4-F-3-PBA], trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid [trans-DCCA]) in first morning void urine, collected from 68 children from New Orleans, Louisiana residing in green and non-green housing was conducted. Children were followed for 1 year with three repeated measures of pesticide exposure. Generalized estimating equations examined associations between housing type (green vs. non-green) and urinary pyrethroid metabolite concentrations adjusting for demographic and household factors over the year. Ninety-five percent of samples had detectable concentrations of 3-PBA (limit of detection [LOD]: 0.1 μg/L); 8% of 4-F-3-PBA (LOD: 0.1 μg/L), and 12% of trans-DCCA (LOD: 0.6 μg/L). In adjusted models, green housing was not associated with statistically significant differences in children's 3-PBA urinary concentrations compared to non-green housing.
Sections du résumé
BACKGROUND
There is growing concern about children's chronic low-level pesticide exposure and its impact on health. Green building practices (e.g., reducing leakage of the thermal and pressure barrier that surrounds the structure, integrated pest management, improved ventilation) have the potential to reduce pesticide exposure. However, the potential impact of living in green housing on children's pesticide exposure is unknown.
OBJECTIVE
To address this question, a longitudinal study of pyrethroid metabolites (3-phenoxybenzoic acid [3-PBA], 4-fluoro-3-phenoxybenzoic acid [4-F-3-PBA], trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid [trans-DCCA]) in first morning void urine, collected from 68 children from New Orleans, Louisiana residing in green and non-green housing was conducted.
METHODS
Children were followed for 1 year with three repeated measures of pesticide exposure. Generalized estimating equations examined associations between housing type (green vs. non-green) and urinary pyrethroid metabolite concentrations adjusting for demographic and household factors over the year.
RESULTS
Ninety-five percent of samples had detectable concentrations of 3-PBA (limit of detection [LOD]: 0.1 μg/L); 8% of 4-F-3-PBA (LOD: 0.1 μg/L), and 12% of trans-DCCA (LOD: 0.6 μg/L). In adjusted models, green housing was not associated with statistically significant differences in children's 3-PBA urinary concentrations compared to non-green housing.
Identifiants
pubmed: 33677471
doi: 10.1038/s41370-021-00312-w
pii: 10.1038/s41370-021-00312-w
pmc: PMC8140995
mid: NIHMS1673567
doi:
Substances chimiques
Insecticides
0
Pyrethrins
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
549-559Subventions
Organisme : NCEH CDC HHS
ID : U01 EH001130
Pays : United States
Références
J Expo Sci Environ Epidemiol. 2020 May;30(3):547-553
pubmed: 30926895
Public Health Rep. 2009 Jan-Feb;124(1):149-59
pubmed: 19413037
J Expo Sci Environ Epidemiol. 2011 May-Jun;21(3):317-27
pubmed: 20407476
Environ Int. 2018 Oct;119:89-99
pubmed: 29944988
Environ Health Perspect. 2006 Jun;114(6):961-8
pubmed: 16760001
Annu Rev Public Health. 2018 Apr 1;39:291-308
pubmed: 29328864
Pediatr Ann. 2004 Jul;33(7):474-81
pubmed: 15298313
Environ Sci Technol. 2009 Jun 15;43(12):4294-300
pubmed: 19603637
Curr Environ Health Rep. 2015 Sep;2(3):250-8
pubmed: 26231502
J Thorac Dis. 2015 Nov;7(11):E537-40
pubmed: 26716051
Int J Hyg Environ Health. 2015 Jul;218(5):479-88
pubmed: 25891895
Toxicol Lett. 2012 Apr 25;210(2):155-68
pubmed: 22020228
Am J Public Health. 2015 Dec;105(12):2482-9
pubmed: 26469661
Sci Total Environ. 2017 Jan 1;575:525-535
pubmed: 27614863
Environ Int. 2018 Dec;121(Pt 2):1148-1154
pubmed: 30808487
Int J Environ Res Public Health. 2011 May;8(5):1727-54
pubmed: 21655147
Occup Environ Med. 2015 Feb;72(2):81-2
pubmed: 25540410
J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jun 15;929:18-26
pubmed: 23648311
Environ Int. 2017 Dec;109:114-127
pubmed: 28916131
Int J Environ Res Public Health. 2017 Mar 04;14(3):
pubmed: 28273865
Environ Pollut. 2020 Dec;267:115489
pubmed: 33254662
Environ Health Perspect. 2014 Feb;122(2):201-6
pubmed: 24325925
Int J Hyg Environ Health. 2015 May;218(3):281-92
pubmed: 25648288
Stat Med. 2008 Sep 10;27(20):4094-106
pubmed: 18344178
Environ Sci Technol. 2013 Jan 15;47(2):859-67
pubmed: 23244175
Occup Environ Med. 2005 Nov;62(11):750-60
pubmed: 16234400
Indoor Air. 2014 Aug;24(4):390-402
pubmed: 24387593
Eur Respir Rev. 2015 Sep;24(137):462-73
pubmed: 26324808
Food Chem Toxicol. 2013 Feb;52:91-6
pubmed: 23146693
Adv Data. 2000 Jun 8;(314):1-27
pubmed: 11183293
Environ Health. 2013 Aug 20;12:65
pubmed: 23962276
Environ Health Perspect. 2010 Jun;118(6):742-8
pubmed: 20129874
Am J Public Health. 2011 Dec;101 Suppl 1:S238-45
pubmed: 21836112
Int J Environ Res Public Health. 2011 May;8(5):1402-19
pubmed: 21655127
Annu Rev Public Health. 2015 Mar 18;36:89-108
pubmed: 25785886
Curr Environ Health Rep. 2019 Mar;6(1):16-21
pubmed: 30701410
Environ Health Perspect. 2017 Jul 31;125(7):075001
pubmed: 28796634
Crit Rev Toxicol. 2018 Apr;48(4):297-311
pubmed: 29389244
Environ Health Perspect. 2015 Oct;123(10):1086-93
pubmed: 25861095
Environ Sci Technol. 2013 Feb 19;47(4):2018-25
pubmed: 23363037
Ann N Y Acad Sci. 2008;1136:276-88
pubmed: 18579887
J Environ Health. 2014 Mar;76(7):8-16; quiz 60
pubmed: 24683934