Cerebrospinal fluid cannot be used to distinguish inflammatory myelitis from congestive myelopathy due to spinal dural arteriovenous fistula: case series.

CSF MRI myelopathy neuropathology neuroradiology

Journal

BMJ neurology open
ISSN: 2632-6140
Titre abrégé: BMJ Neurol Open
Pays: England
ID NLM: 101775450

Informations de publication

Date de publication:
2019
Historique:
accepted: 11 12 2019
entrez: 8 3 2021
pubmed: 22 12 2019
medline: 22 12 2019
Statut: epublish

Résumé

Patients with congestive myelopathy due to spinal dural arteriovenous fistula (SDAVF) typically present with progressive sensory and motor disturbance in association with sphincter dysfunction. Spinal MRI usually shows longitudinally extensive T2 signal change. Here, we report four patients with progressive myelopathy due to SDAVF who also presented with findings on cerebrospinal fluid (CSF) examination suggestive of an inflammatory aetiology. Such CSF findings in SDAVF are important to recognise, to avoid the erroneous diagnosis of an inflammatory myelitis and inappropriate treatment with immunosuppression. SDAVF can be difficult to detect and may require repeated investigation, with formal angiography as the gold standard.

Identifiants

pubmed: 33681770
doi: 10.1136/bmjno-2019-000019
pii: bmjno-2019-000019
pmc: PMC7871706
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e000019

Informations de copyright

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Vinojini Vivekanandam (V)

National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Vivien Li (V)

National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.

Teddy Wu (T)

Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Neurology, Christchurch Hospital, Christchurch, New Zealand.

Richard Dowling (R)

Radiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Richard H Roxburgh (RH)

Neurology, Auckland City Hospital, Auckland, Auckland, New Zealand.

Ben J McGuiness (BJ)

Radiology, Auckland City Hospital, Auckland, Auckland, New Zealand.

Dean H Kilfoyle (DH)

Neurology, Auckland City Hospital, Auckland, Auckland, New Zealand.

Hadi Manji (H)

National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.

Annelies Quaegebeur (A)

Neuropathology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.

Maria Thom (M)

Neuropathology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.

Fergus Robertson (F)

Neuroradiology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, United Kingdom.

Wesley Thevathasan (W)

Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Andrew Evans (A)

Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Stefan Brew (S)

Radiology, Auckland City Hospital, Auckland, Auckland, New Zealand.

Peter Mitchell (P)

Radiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Classifications MeSH