Volumetric histograms-based analysis of apparent diffusion coefficients and standard uptake values for the assessment of pediatric sarcoma at staging: preliminary results of a PET/MRI study.
ADC
Histograms
PET/MRI
Pediatric sarcoma
SUV
Journal
La Radiologia medica
ISSN: 1826-6983
Titre abrégé: Radiol Med
Pays: Italy
ID NLM: 0177625
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
14
08
2020
accepted:
21
02
2021
pubmed:
9
3
2021
medline:
1
6
2021
entrez:
8
3
2021
Statut:
ppublish
Résumé
To assess the relationship between apparent diffusion coefficients (ADC) and standard uptake values (SUV) of pediatric sarcomas at staging by using volumetric histograms analyses. Children with histologically proven sarcoma, referring to our tertiary center for a whole-body Thirteen patients met the inclusion criteria (six females; mean age 8.31 ± 6.03 years). Histology revealed nine rhabdomyosarcomas, three Ewing sarcomas, and one chondroblastic osteosarcoma. A significant negative correlation between ADCs' and SUVs' mean (r Our preliminary results demonstrate that, using volumetric histograms, simultaneously collected SUVs and ADCs are dependent biomarkers in pediatric FDG-avid sarcomas. Further studies, on a larger population, are necessary to confirm this evidence and assess its clinical implications.
Identifiants
pubmed: 33683542
doi: 10.1007/s11547-021-01340-0
pii: 10.1007/s11547-021-01340-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
878-885Références
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