"Lighten This Burden of Ours": Acceptability and Preferences Regarding Injectable Antiretroviral Treatment Among Adults and Youth Living With HIV in Coastal Kenya.
Africa
HIV/AIDS
Kenya
acceptability
long-acting injectable ART
qualitative
Journal
Journal of the International Association of Providers of AIDS Care
ISSN: 2325-9582
Titre abrégé: J Int Assoc Provid AIDS Care
Pays: United States
ID NLM: 101603896
Informations de publication
Date de publication:
Historique:
entrez:
9
3
2021
pubmed:
10
3
2021
medline:
29
7
2021
Statut:
ppublish
Résumé
Long-acting injectable (LAI) antiretroviral therapy (ART) may offer persons living with HIV (PLWH) an attractive alternative to pill-based treatment options, yet acceptability data remain scant, especially in sub-Saharan Africa. We conducted 6 focus group discussions with PLWH, including key stake holder groups, and analyzed data with content analysis. Initial reactions to the idea of LAI-ART were often positive. The primary advantages voiced were potential to facilitate improved adherence and alleviate the burden of daily pill-taking while avoiding inadvertent disclosure and HIV stigma. Potential side effects were a particular concern of the women. Most participants preferred clinic-based administration over self-injections at home due to concerns about safety, privacy, and potential need for refrigeration. LAI-ART may be acceptable in Kenya, provided injections are infrequent and delivered in a clinic setting. However, HIV stigma, fear of potential side effects, and limited clinical capacity would need to be addressed.
Sections du résumé
BACKGROUND
Long-acting injectable (LAI) antiretroviral therapy (ART) may offer persons living with HIV (PLWH) an attractive alternative to pill-based treatment options, yet acceptability data remain scant, especially in sub-Saharan Africa.
METHODS
We conducted 6 focus group discussions with PLWH, including key stake holder groups, and analyzed data with content analysis.
RESULTS
Initial reactions to the idea of LAI-ART were often positive. The primary advantages voiced were potential to facilitate improved adherence and alleviate the burden of daily pill-taking while avoiding inadvertent disclosure and HIV stigma. Potential side effects were a particular concern of the women. Most participants preferred clinic-based administration over self-injections at home due to concerns about safety, privacy, and potential need for refrigeration.
CONCLUSIONS
LAI-ART may be acceptable in Kenya, provided injections are infrequent and delivered in a clinic setting. However, HIV stigma, fear of potential side effects, and limited clinical capacity would need to be addressed.
Identifiants
pubmed: 33685272
doi: 10.1177/23259582211000517
pmc: PMC7952847
doi:
Substances chimiques
Anti-HIV Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
23259582211000517Subventions
Organisme : NIAID NIH HHS
ID : P30 AI027757
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH121424
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI120176
Pays : United States
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