High sensitivity troponin and COVID-19 outcomes.

COVID-19 / complications Hospitalization Humans Respiration, Artificial SARS-CoV-2 Troponin / blood
COVID-19 Troponin cardiovascular disease outcomes

Journal

Acta cardiologica
ISSN: 1784-973X
Titre abrégé: Acta Cardiol
Pays: England
ID NLM: 0370570

Informations de publication

Date de publication:
Feb 2022
Historique:
pubmed: 10 3 2021
medline: 2 4 2022
entrez: 9 3 2021
Statut: ppublish

Résumé

Recent reports have demonstrated high troponin levels in patients affected with COVID-19. In the present study, we aimed to determine the association between admission and peak troponin levels and COVID-19 outcomes. This was an observational multi-ethnic multi-centre study in a UK cohort of 434 patients admitted and diagnosed COVID-19 positive, across six hospitals in London, UK during the second half of March 2020. Myocardial injury, defined as positive troponin during admission was observed in 288 (66.4%) patients. Age (OR: 1.68 [1.49-1.88], Admission and peak troponin appear to be predictors for cardiovascular and non-cardiovascular events and outcomes in COVID-19 patients, and their utilisation may have an impact on patient management.

Sections du résumé

BACKGROUND BACKGROUND
Recent reports have demonstrated high troponin levels in patients affected with COVID-19. In the present study, we aimed to determine the association between admission and peak troponin levels and COVID-19 outcomes.
METHODS METHODS
This was an observational multi-ethnic multi-centre study in a UK cohort of 434 patients admitted and diagnosed COVID-19 positive, across six hospitals in London, UK during the second half of March 2020.
RESULTS RESULTS
Myocardial injury, defined as positive troponin during admission was observed in 288 (66.4%) patients. Age (OR: 1.68 [1.49-1.88],
CONCLUSIONS CONCLUSIONS
Admission and peak troponin appear to be predictors for cardiovascular and non-cardiovascular events and outcomes in COVID-19 patients, and their utilisation may have an impact on patient management.

Identifiants

DOI: 10.1080/00015385.2021.1887586 PMID: 33685354 PMC: PMC7970632
pubmed: 33685354
doi: 10.1080/00015385.2021.1887586
pmc: PMC7970632
doi:

Substances chimiques

Troponin 0

Types de publication

Journal Article Multicenter Study Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

81-88

Auteurs

Nikolaos Papageorgiou (N)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
Institute of Cardiovascular Science, University College London, London, UK.

Catrin Sohrabi (C)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
ORCID: 0000-0003-2773-5659

David Prieto Merino (D)

Department of Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Applied Statistics in Medical Research Group, Catholic University of Murcia (UCAM), Murcia, Spain.
ORCID: 0000-0001-5001-0061

Angelos Tyrlis (A)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Abed Elfattah Atieh (AE)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Bunny Saberwal (B)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Wei-Yao Lim (WY)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Antonio Creta (A)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Mohammed Khanji (M)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Reni Rusinova (R)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Bashistraj Chooneea (B)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Raj Khiani (R)

Applied Statistics in Medical Research Group, Catholic University of Murcia (UCAM), Murcia, Spain.
Barnett Hospital, London, UK.

Nadeev Wijesuriya (N)

Barnett Hospital, London, UK.
Royal Free Hospital, London, UK.

Anna Chow (A)

Barnett Hospital, London, UK.
Royal Free Hospital, London, UK.

Haroun Butt (H)

Barnett Hospital, London, UK.
Royal Free Hospital, London, UK.

Stefan Browne (S)

Barnett Hospital, London, UK.
Royal Free Hospital, London, UK.

Nikhil Joshi (N)

Barnett Hospital, London, UK.
Royal Free Hospital, London, UK.

Jamie Kay (J)

Barnett Hospital, London, UK.
Royal Free Hospital, London, UK.

Syed Ahsan (S)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.

Rui Providencia (R)

St. Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
Institute of Health Informatics Research, University College of London, London, UK.
ORCID: 0000-0001-9141-9883

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Classifications MeSH

questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › High sensitivity troponin and COVID-19 outcomes.
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Soins aux patients › Hospitalisation › High sensitivity troponin and COVID-19 outcomes.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › High sensitivity troponin and COVID-19 outcomes.
questionsmedicales.fr › Thérapeutique › Thérapie respiratoire › Ventilation artificielle › High sensitivity troponin and COVID-19 outcomes.
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Virus du SRAS › SARS-CoV-2 › High sensitivity troponin and COVID-19 outcomes.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cytosquelette › Protéines des microfilaments › Troponine › High sensitivity troponin and COVID-19 outcomes.