Presence of microorganisms in children with pharyngotonsillitis and healthy controls: a prospective study in primary healthcare.
Aetiology
Children
PCR
Pharyngotonsillitis
Primary healthcare
Prospective
Journal
Infection
ISSN: 1439-0973
Titre abrégé: Infection
Pays: Germany
ID NLM: 0365307
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
09
12
2020
accepted:
23
02
2021
pubmed:
10
3
2021
medline:
26
11
2021
entrez:
9
3
2021
Statut:
ppublish
Résumé
Most studies on paediatric pharyngotonsillitis focus on group A streptococci. This study, however, analyses a broad spectrum of bacteria and viruses related to paediatric pharyngotonsillitis and evaluates their associated clinical symptoms and courses. This observational prospective study in primary healthcare includes 77 children aged < 15 with a sore throat and 34 asymptomatic children, all of whom were sampled from the tonsils with an E-swab A pathogen was detected in 86% of patients and in 71% of controls (P = 0.06). Bacteria were found in 69% of patients and 59% of controls (P = 0.3), and viruses in 36% and 26%, respectively (P = 0.3). Group A streptococci was the most common finding, with a prevalence of 49% and 32%, respectively (P = 0.1). Clinical signs were not useful for distinguishing pathogens. None of the controls and 16% of the patients reconsulted for a sore throat within 3 months. Bacteria were more common than viruses in both study groups. The high rate of pathogens in asymptomatic children interferes with diagnoses based on aetiology.
Identifiants
pubmed: 33686635
doi: 10.1007/s15010-021-01595-9
pii: 10.1007/s15010-021-01595-9
pmc: PMC7938884
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
715-724Informations de copyright
© 2021. The Author(s).
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