Serological evidence of SARS-CoV-2 and co-infections in stray cats in Spain.
COVID-19
ELISA
SARS-CoV-2
concomitant infections
serology
stray cats
Journal
Transboundary and emerging diseases
ISSN: 1865-1682
Titre abrégé: Transbound Emerg Dis
Pays: Germany
ID NLM: 101319538
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
revised:
09
02
2021
received:
22
11
2020
accepted:
05
03
2021
pubmed:
10
3
2021
medline:
7
5
2022
entrez:
9
3
2021
Statut:
ppublish
Résumé
A new coronavirus known as SARS-CoV-2 emerged in Wuhan in 2019 and spread rapidly to the rest of the world causing the pandemic disease named coronavirus disease of 2019 (COVID-19). Little information is known about the impact this virus can cause upon domestic and stray animals. The potential impact of SARS-CoV-2 has become of great interest in cats due to transmission among domestic cats and the severe phenotypes described recently in a domestic cat. In this context, there is a public health warning that needs to be investigated in relation with the epidemiological role of this virus in stray cats. Consequently, in order to know the impact of the possible transmission chain, blood samples were obtained from 114 stray cats in the city of Zaragoza (Spain) and tested for SARS-CoV-2 and other selected pathogens susceptible to immunosuppression including Toxoplasma gondii, Leishmania infantum, feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) from January to October 2020. Four cats (3.51%), based on enzyme-linked immunosorbent assay (ELISA) using the receptor binding domain (RBD) of Spike antigen, were seroreactive to SARS-CoV-2. T. gondii, L. infantum, FeLV and FIV seroprevalence was 12.28%, 16.67%, 4.39% and 19.30%, respectively. Among seropositive cats to SARS-CoV-2, three cats were also seropositive to other pathogens including antibodies detected against T. gondii and FIV (n = 1); T. gondii (n = 1); and FIV and L. infantum (n = 1). The subjects giving positive for SARS-CoV-2 were captured in urban areas of the city in different months: January 2020 (2/4), February 2020 (1/4) and July 2020 (1/4). This study revealed, for the first time, the exposure of stray cats to SARS-CoV-2 in Spain and the existence of concomitant infections with other pathogens including T. gondii, L. infantum and FIV, suggesting that immunosuppressed animals might be especially susceptible to SARS-CoV-2 infection.
Identifiants
pubmed: 33686768
doi: 10.1111/tbed.14062
pmc: PMC8250530
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1056-1064Subventions
Organisme : MCNU
ID : CTQ2013-44367-C2-2-P
Organisme : MCNU
ID : BFU2016-75633-P
Organisme : MCNU
ID : PID2019-105451GB-I00
Organisme : Gobierno de Aragón
ID : E34_R17
Organisme : Gobierno de Aragón
ID : LMP58_18
Organisme : Fondo Europeo de Desarrollo Regional, Gobierno de Aragón
ID : Group B29_17R
Organisme : Agencia Estatal de Investigación
ID : SAF2017-83120-C2-1-R
Informations de copyright
© 2021 Wiley-VCH GmbH.
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