Tonsillar Microbiota: a Cross-Sectional Study of Patients with Chronic Tonsillitis or Tonsillar Hypertrophy.
16S rRNA gene sequencing
chronic tonsillitis
microbiota
tonsillar hypertrophy
tonsillar tissues
Journal
mSystems
ISSN: 2379-5077
Titre abrégé: mSystems
Pays: United States
ID NLM: 101680636
Informations de publication
Date de publication:
09 Mar 2021
09 Mar 2021
Historique:
entrez:
10
3
2021
pubmed:
11
3
2021
medline:
11
3
2021
Statut:
epublish
Résumé
Chronic tonsillitis (CT) and tonsillar hypertrophy (TH) are common tonsillar diseases that are related to infection and inflammation. Little is known about tonsillar microbiota and its role in CT and TH. This study aims to identify palatine tonsillar microbiota both on the surface and in the core tissues of CT and TH patients. In total, 22 palatine tonsils were removed and collected from CT and TH patients who underwent surgery. The surface and core microbiota in the tonsils of CT and TH patients were compared using 16S rRNA gene sequencing of V3-V4 regions. Differential tonsillar microbiotas were found in the CT versus TH patients and surface versus core tissues. Further, a higher relative abundance of bacterial genera, including
Identifiants
pubmed: 33688019
pii: 6/2/e01302-20
doi: 10.1128/mSystems.01302-20
pmc: PMC8547005
pii:
doi:
Types de publication
Journal Article
Langues
eng
Informations de copyright
Copyright © 2021 Wu et al.
Références
Can J Infect Dis Med Microbiol. 2018 Nov 1;2018:5406467
pubmed: 30515253
Pediatrics. 2002 Jul;110(1 Pt 1):7-15
pubmed: 12093941
Nat Methods. 2013 Oct;10(10):996-8
pubmed: 23955772
Microb Ecol Health Dis. 2015 May 29;26:27663
pubmed: 26028277
Int J Pediatr Otorhinolaryngol. 2016 Jul;86:57-9
pubmed: 27260580
Appl Environ Microbiol. 2005 Dec;71(12):8228-35
pubmed: 16332807
Nature. 2011 May 12;473(7346):174-80
pubmed: 21508958
Nat Methods. 2010 May;7(5):335-6
pubmed: 20383131
Int J Pediatr Otorhinolaryngol. 2018 Oct;113:51-57
pubmed: 30174010
Oral Dis. 2006 Jul;12(4):371-4
pubmed: 16792721
Int J Pediatr Otorhinolaryngol. 2018 Oct;113:281-288
pubmed: 30174001
Clin Transl Allergy. 2018 May 22;8:22
pubmed: 29942488
Bioinformatics. 2014 Aug 1;30(15):2114-20
pubmed: 24695404
Pediatr Clin North Am. 1989 Dec;36(6):1551-69
pubmed: 2685730
Front Microbiol. 2017 Mar 01;8:276
pubmed: 28298903
J Oral Microbiol. 2016 Mar 15;8:30989
pubmed: 26983837
J Clin Diagn Res. 2016 Nov;10(11):MC01-MC03
pubmed: 28050412
Int J Pediatr Otorhinolaryngol. 2005 Jan;69(1):9-19
pubmed: 15627441
Nat Rev Microbiol. 2017 May;15(5):259-270
pubmed: 28316330
Cell Host Microbe. 2017 Sep 13;22(3):269-278.e3
pubmed: 28910633
Nat Biotechnol. 2020 Jun;38(6):685-688
pubmed: 32483366
Int J Pediatr Otorhinolaryngol. 2015 Feb;79(2):191-5
pubmed: 25555639
Bioinformatics. 2016 Jul 1;32(13):2038-40
pubmed: 27153704
Front Microbiol. 2017 Nov 15;8:2244
pubmed: 29187843
Bioinformatics. 2010 Oct 1;26(19):2460-1
pubmed: 20709691
BMC Microbiol. 2016 Apr 01;16 Suppl 1:57
pubmed: 27036492
Bioinformatics. 2011 Nov 1;27(21):2957-63
pubmed: 21903629
Mov Disord. 2017 May;32(5):739-749
pubmed: 28195358
mSystems. 2018 Dec 4;3(6):
pubmed: 30534599
Nat Commun. 2019 Nov 6;10(1):5029
pubmed: 31695033
J Antimicrob Chemother. 1997 Jun;39(6):763-9
pubmed: 9222046
Eur Arch Otorhinolaryngol. 2017 Aug;274(8):3153-3159
pubmed: 28551703
Laryngoscope. 2007 Dec;117(12):2146-51
pubmed: 17909446
Front Cell Infect Microbiol. 2019 Mar 20;9:59
pubmed: 30949454
Int J Pediatr Otorhinolaryngol. 1998 Feb;43(1):33-9
pubmed: 9596368
FEMS Microbiol Lett. 2005 Sep 15;250(2):279-85
pubmed: 16099112
BMC Oral Health. 2019 Dec 5;19(1):275
pubmed: 31806002
Microbes Infect. 2008 Apr;10(5):489-96
pubmed: 18403243
Nucleic Acids Res. 2004 Jan 1;32(Database issue):D277-80
pubmed: 14681412
J Clin Microbiol. 2009 Mar;47(3):848-51
pubmed: 19109480
Int J Pediatr Otorhinolaryngol. 2020 Jun;133:110004
pubmed: 32200310
Sci Rep. 2016 Jul 27;6:30388
pubmed: 27461975
PLoS One. 2013;8(2):e56418
pubmed: 23437130