Genetic diversity and antifungal susceptibility of Candida albicans isolates from Iranian HIV-infected patients with oral candidiasis.
Antifungal susceptibility
Candida albicans
Genetic diversity
HIV+ patients
RAPD-PCR
Journal
BMC research notes
ISSN: 1756-0500
Titre abrégé: BMC Res Notes
Pays: England
ID NLM: 101462768
Informations de publication
Date de publication:
10 Mar 2021
10 Mar 2021
Historique:
received:
12
11
2020
accepted:
23
02
2021
entrez:
11
3
2021
pubmed:
12
3
2021
medline:
15
5
2021
Statut:
epublish
Résumé
The objectives of this study were to investigate the antifungal susceptibility and genetic diversity of Candida albicans isolated from HIV The inhibition zones ranged from 4 ± 1.8 to 40 ± 3.8 mm for fluconazole, 7 ± 1.0 to 37 ± 1.8 mm for ketoconazole, 14 ± 0.8 to24 ± 0.8 mm for amphotericin B, 25 ± 0.0 to 33 ± 0.0 mm for nystatin and 7 ± 4.2 to 40 ± 0.0 mm for clotrimazole. At 90% similarity, three distinct groups were observed. The smallest cluster composed of 3 isolates, whereas the largest one composed of 17 isolates. 32% (16/50), 28% (14/50) and 14% (7/50) were resistant to fluconazole, ketoconazole and clotrimazole, respectively.
Identifiants
pubmed: 33691787
doi: 10.1186/s13104-021-05498-8
pii: 10.1186/s13104-021-05498-8
pmc: PMC7945322
doi:
Substances chimiques
Antifungal Agents
0
Fluconazole
8VZV102JFY
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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