Characteristics of Inter-Arm Difference in Blood Pressure in Acute Aortic Dissection.


Journal

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
ISSN: 1347-3409
Titre abrégé: J Nippon Med Sch
Pays: Japan
ID NLM: 100935589

Informations de publication

Date de publication:
17 Nov 2021
Historique:
pubmed: 12 3 2021
medline: 18 1 2022
entrez: 11 3 2021
Statut: ppublish

Résumé

An inter-arm difference in blood pressure (IADBP) is characteristic of acute aortic dissection (AAD), but the importance of which arm exhibits lower blood pressure (BP) and the mechanism underlying IADBP are not well understood. We identified consecutive patients with chest and/or back pain and suspected acute cardiovascular disease whose BP had been measured in both arms. We retrospectively compared the characteristics of such patients with AAD (n=93) to those without AAD (non-AAD group, n=122). Additionally, we separately compared patients with type A AAD (TAAD group, n=58) or type B AAD (TBAD group, n=35) to the non-AAD group. The characteristics analyzed were patient background and IADBP-related factors, including systolic BP (SBP) in the right arm (R) and left arm (L), and R-L or L-R as IADBP. Computed tomography (CT) findings of AD extending to the brachiocephalic artery (BCA) and/or left subclavian artery (LSCA) were examined in patients with an IADBP. In a comparison of the TAAD group and non-AAD group, the prevalences of R <130 mm Hg (38% vs. 19%, p=0.009), L-R >15 mm Hg (19% vs. 8%, p=0.047), L-R >20 mm Hg (14% vs. 4%, p=0.029) were higher in the TAAD group. Multivariate analysis showed that L-R >15 mm Hg with R <130 mm Hg was independently associated with TAAD (OR 25.97, 95% CI 2.45-275.67, p=0.007). However, IADBP-related factors were not associated with TBAD. AAD patients with L-R >20 mm Hg all had TAAD, and all aortic dissection extended to the BCA just before the right common carotid artery on CT. IADBP was characterized by R<L with low R in TAAD but was not associated with TBAD.

Sections du résumé

BACKGROUND BACKGROUND
An inter-arm difference in blood pressure (IADBP) is characteristic of acute aortic dissection (AAD), but the importance of which arm exhibits lower blood pressure (BP) and the mechanism underlying IADBP are not well understood.
METHODS METHODS
We identified consecutive patients with chest and/or back pain and suspected acute cardiovascular disease whose BP had been measured in both arms. We retrospectively compared the characteristics of such patients with AAD (n=93) to those without AAD (non-AAD group, n=122). Additionally, we separately compared patients with type A AAD (TAAD group, n=58) or type B AAD (TBAD group, n=35) to the non-AAD group. The characteristics analyzed were patient background and IADBP-related factors, including systolic BP (SBP) in the right arm (R) and left arm (L), and R-L or L-R as IADBP. Computed tomography (CT) findings of AD extending to the brachiocephalic artery (BCA) and/or left subclavian artery (LSCA) were examined in patients with an IADBP.
RESULTS RESULTS
In a comparison of the TAAD group and non-AAD group, the prevalences of R <130 mm Hg (38% vs. 19%, p=0.009), L-R >15 mm Hg (19% vs. 8%, p=0.047), L-R >20 mm Hg (14% vs. 4%, p=0.029) were higher in the TAAD group. Multivariate analysis showed that L-R >15 mm Hg with R <130 mm Hg was independently associated with TAAD (OR 25.97, 95% CI 2.45-275.67, p=0.007). However, IADBP-related factors were not associated with TBAD. AAD patients with L-R >20 mm Hg all had TAAD, and all aortic dissection extended to the BCA just before the right common carotid artery on CT.
CONCLUSIONS CONCLUSIONS
IADBP was characterized by R<L with low R in TAAD but was not associated with TBAD.

Identifiants

pubmed: 33692296
doi: 10.1272/jnms.JNMS.2021_88-605
doi:

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

467-474

Auteurs

Nozomi Sasamoto (N)

Department of Cardiovascular Medicine, Nippon Medical School.
Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Koichi Akutsu (K)

Department of Cardiovascular Medicine, Nippon Medical School.
Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Takeshi Yamamoto (T)

Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Toshiaki Otsuka (T)

Department of Hygiene and Public Health, Nippon Medical School.
Center for Clinical Research, Nippon Medical School Hospital.

Hideto Sangen (H)

Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Hiroshi Hayashi (H)

Department of Cardiovascular Medicine, Nippon Medical School.
Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Hiroshige Murata (H)

Department of Cardiovascular Medicine, Nippon Medical School.
Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Hideki Miyachi (H)

Department of Cardiovascular Medicine, Nippon Medical School.
Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Yusuke Hosokawa (Y)

Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Shuhei Tara (S)

Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Yukichi Tokita (Y)

Department of Cardiovascular Medicine, Nippon Medical School.
Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

Satoshi Miyata (S)

Teikyo University Graduate School of Public Healt.

Tetsuro Morota (T)

Department of Cardiovascular Surgery, Nippon Medical School.

Takashi Nitta (T)

Department of Cardiovascular Surgery, Nippon Medical School.

Wataru Shimizu (W)

Department of Cardiovascular Medicine, Nippon Medical School.
Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.

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