Serum NGAL, BNP, PTH, and albumin do not improve glomerular filtration rate estimating formulas in children.
Albumin
Brain natriuretic peptide
Child
Glomerular filtration rate
Neutrophil gelatinase-associated lipocalin
Parathyroid hormone
Journal
European journal of pediatrics
ISSN: 1432-1076
Titre abrégé: Eur J Pediatr
Pays: Germany
ID NLM: 7603873
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
18
08
2020
accepted:
04
03
2021
revised:
02
03
2021
pubmed:
12
3
2021
medline:
24
6
2021
entrez:
11
3
2021
Statut:
ppublish
Résumé
Glomerular filtration rate (GFR) is difficult to measure, and estimating formulas are notorious for lacking precision. This study aims to assess if the inclusion of additional biomarkers improves the performance of eGFR formulas. A hundred and sixteen children with renal diseases were enrolled. Data for age, weight, height, inulin clearance (iGFR), serum creatinine, cystatin C, neutrophil gelatinase-associated lipocalin (NGAL), parathyroid hormone (PTH), albumin, and brain natriuretic peptide (BNP) were collected. These variables were added to the revised and combined (serum creatinine and cystatin C) Schwartz formulas, and the quadratic and combined quadratic formulas. We calculated the adjusted r-square (r
Identifiants
pubmed: 33693979
doi: 10.1007/s00431-021-04019-w
pii: 10.1007/s00431-021-04019-w
pmc: PMC8195898
doi:
Substances chimiques
Albumins
0
Biomarkers
0
Lipocalin-2
0
Parathyroid Hormone
0
Natriuretic Peptide, Brain
114471-18-0
Creatinine
AYI8EX34EU
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2223-2228Références
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