Differential diagnoses of COVID-19 pneumonia: the current challenge for the radiologist-a pictorial essay.

COVID-19 Computed tomography Coronavirus Differential diagnosis Pneumonia

Journal

Insights into imaging
ISSN: 1869-4101
Titre abrégé: Insights Imaging
Pays: Germany
ID NLM: 101532453

Informations de publication

Date de publication:
11 Mar 2021
Historique:
received: 25 09 2020
accepted: 12 01 2021
entrez: 11 3 2021
pubmed: 12 3 2021
medline: 12 3 2021
Statut: epublish

Résumé

COVID-19 pneumonia represents the most severe pandemic of the twenty-first century and has crucial clinical, social and economical implications. The scientific community has focused attention and resources on clinical and radiological features of COVID-19 pneumonia. Few papers analysing the vast spectrum of differential diagnoses have been published. Complexity of differential diagnosis lays in the evidence of similar radiological findings as ground-glass opacities, crazy paving pattern and consolidations in COVID-19 pneumonia and a multitude of other lung diseases. Differential diagnosis is and will be extremely important during and after the pandemic peak, when there are fewer COVID-19 pneumonia cases. The aim of our pictorial essay is to schematically present COVID-19 pneumonia most frequent differential diagnoses to help the radiologist face the current COVID-19 pneumonia challenge. Clinical data, laboratory tests and imaging are pillars of a trident, which allows to reach a correct diagnosis in order to grant an excellent allocation of human and economical resources. The radiologist has a pivotal role in the early diagnosis of COVID-19 pneumonia because he may raise suspicion of the pathology and help to avoid COVID-19 virus spread.

Sections du résumé

BACKGROUND BACKGROUND
COVID-19 pneumonia represents the most severe pandemic of the twenty-first century and has crucial clinical, social and economical implications. The scientific community has focused attention and resources on clinical and radiological features of COVID-19 pneumonia. Few papers analysing the vast spectrum of differential diagnoses have been published.
MAIN BODY METHODS
Complexity of differential diagnosis lays in the evidence of similar radiological findings as ground-glass opacities, crazy paving pattern and consolidations in COVID-19 pneumonia and a multitude of other lung diseases. Differential diagnosis is and will be extremely important during and after the pandemic peak, when there are fewer COVID-19 pneumonia cases. The aim of our pictorial essay is to schematically present COVID-19 pneumonia most frequent differential diagnoses to help the radiologist face the current COVID-19 pneumonia challenge.
CONCLUSIONS CONCLUSIONS
Clinical data, laboratory tests and imaging are pillars of a trident, which allows to reach a correct diagnosis in order to grant an excellent allocation of human and economical resources. The radiologist has a pivotal role in the early diagnosis of COVID-19 pneumonia because he may raise suspicion of the pathology and help to avoid COVID-19 virus spread.

Identifiants

pubmed: 33704615
doi: 10.1186/s13244-021-00967-x
pii: 10.1186/s13244-021-00967-x
pmc: PMC7948690
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

34

Références

Radiology. 2014 Mar;270(3):681-96
pubmed: 24568704
Radiographics. 1999 Nov-Dec;19(6):1507-31; discussion 1532-3
pubmed: 10555672
Radiology. 2000 Sep;216(3):773-80
pubmed: 10966710
Radiology. 2020 Aug;296(2):E113-E114
pubmed: 32105562
Lancet. 2020 Feb 15;395(10223):514-523
pubmed: 31986261
Nature. 2020 Mar;579(7798):270-273
pubmed: 32015507
Am J Emerg Med. 2003 Jan;21(1):32-4
pubmed: 12563576
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
Can Assoc Radiol J. 2020 May;71(2):195-200
pubmed: 32129670
Radiographics. 2000 Sep-Oct;20(5):1245-59
pubmed: 10992015
Radiology. 2020 Apr;295(1):202-207
pubmed: 32017661
Radiology. 2020 Jul;296(1):172-180
pubmed: 32255413
Clin Radiol. 2018 Nov;73(11):913-921
pubmed: 30075854
Thromb Res. 2020 Dec;196:67-74
pubmed: 32853978
Radiology. 1997 Jun;203(3):715-9
pubmed: 9169693
Radiology. 1990 Jun;175(3):711-4
pubmed: 2343118
Radiographics. 2007 May-Jun;27(3):617-37; discussion 637-9
pubmed: 17495282
J Thromb Haemost. 2020 May;18(5):1020-1022
pubmed: 32239799
Acta Paediatr. 2020 Jun;109(6):1088-1095
pubmed: 32202343
Radiology. 2020 Aug;296(2):E72-E78
pubmed: 32216717
Respir Med. 2018 Dec;145:182-191
pubmed: 30509707
Radiographics. 2001 Jul-Aug;21(4):825-37
pubmed: 11452056
Nat Rev Dis Primers. 2019 Mar 7;5(1):16
pubmed: 30846703
Euro Surveill. 2020 Feb;25(8):
pubmed: 32127123
Medicine (Baltimore). 1988 May;67(3):154-62
pubmed: 3285120
Radiographics. 2003 Nov-Dec;23(6):1521-39
pubmed: 14615562
Diagn Interv Imaging. 2020 May;101(5):263-268
pubmed: 32291197
AJR Am J Roentgenol. 2008 Apr;190(4):907-15
pubmed: 18356436
Cardiovasc Revasc Med. 2011 Nov-Dec;12(6):407-11
pubmed: 21514251
Herz. 2020 May;45(3):230-232
pubmed: 32140732
Radiology. 2020 Jun;295(3):200463
pubmed: 32077789
Radiographics. 2009 Nov;29(7):1921-38
pubmed: 19926754
Radiographics. 2007 Jul-Aug;27(4):941-56
pubmed: 17620460
AJR Am J Roentgenol. 2010 Jan;194(1):103-9
pubmed: 20028911
Transplant Proc. 2009 Jul-Aug;41(6):2163-5
pubmed: 19715862
Respir Care. 2012 Apr;57(4):607-12
pubmed: 22472500
N Engl J Med. 2003 Jul 3;349(1):3-4
pubmed: 12840085
J Thorac Imaging. 2003 Oct;18(4):217-24
pubmed: 14561906
J Comput Assist Tomogr. 2004 Sep-Oct;28(5):710-6
pubmed: 15480049
Eur J Radiol. 2008 Mar;65(3):462-7
pubmed: 17537607
Radiographics. 2018 May-Jun;38(3):719-739
pubmed: 29757717
J Infect Chemother. 2007 Feb;13(1):1-7
pubmed: 17334722
Clin Infect Dis. 1998 Apr;26(4):781-803; quiz 804-5
pubmed: 9564455
Am J Respir Crit Care Med. 2002 Jul 15;166(2):215-35
pubmed: 12119235
AJR Am J Roentgenol. 2007 Feb;188(2):334-44
pubmed: 17242239
Radiology. 2008 Jan;246(1):288-97
pubmed: 18096541
J Comput Assist Tomogr. 2003 Jul-Aug;27(4):475-8
pubmed: 12886127
Crit Care Resusc. 2020 Apr 15;22(2):95-97
pubmed: 32294809
AJR Am J Roentgenol. 1999 Jan;172(1):121-8
pubmed: 9888751
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Radiology. 2008 Mar;246(3):697-722
pubmed: 18195376
Eur Respir J. 2000 Jul;16(1):56-60
pubmed: 10933085
J Thromb Haemost. 2020 Jun;18(6):1511-1513
pubmed: 32293083
AJR Am J Roentgenol. 2014 Mar;202(3):479-92
pubmed: 24555584
Semin Ultrasound CT MR. 2012 Dec;33(6):567-79
pubmed: 23168065
J Thorac Imaging. 2018 Sep;33(5):282-294
pubmed: 30036297
Am J Emerg Med. 2004 Jul;22(4):316
pubmed: 15258878
Clin Imaging. 2020 Aug;64:35-42
pubmed: 32302927
N Engl J Med. 2003 Dec 25;349(26):2527-39
pubmed: 14695413
J Thromb Haemost. 2020 May;18(5):1094-1099
pubmed: 32220112
AJR Am J Roentgenol. 2000 Oct;175(4):1019-24
pubmed: 11000156
Am J Respir Crit Care Med. 1994 Nov;150(5 Pt 1):1423-38
pubmed: 7952571
J Comput Assist Tomogr. 1995 Jan-Feb;19(1):48-51
pubmed: 7822547
Radiology. 1990 Oct;177(1):121-5
pubmed: 2399310
J Comput Assist Tomogr. 1994 Sep-Oct;18(5):737-44
pubmed: 8089322
Thorax. 1991 Oct;46(10):738-9
pubmed: 1750024

Auteurs

Alessia Guarnera (A)

Department of Surgical and Medical Sciences and Translational Medicine, Sapienza University of Rome - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy. guarneraalessia@gmail.com.

Pierfrancesco Podda (P)

Department of Radiology, San Giovanni Addolorata Hospital, Via Dell'Amba Aradam 9, 00184, Rome, Italy.

Elena Santini (E)

Department of Radiology, San Giovanni Addolorata Hospital, Via Dell'Amba Aradam 9, 00184, Rome, Italy.

Pasquale Paolantonio (P)

Department of Radiology, San Giovanni Addolorata Hospital, Via Dell'Amba Aradam 9, 00184, Rome, Italy.

Andrea Laghi (A)

Department of Surgical and Medical Sciences and Translational Medicine, Sapienza University of Rome - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.

Classifications MeSH