Immune reconstitution inflammatory syndrome in
Immune reconstitution inflammatory syndrome
Mycobacterium chimaera
mediastinitis
nontuberculous mycobacterium
postoperative cardiovascular infections
Journal
International journal of mycobacteriology
ISSN: 2212-554X
Titre abrégé: Int J Mycobacteriol
Pays: India
ID NLM: 101615660
Informations de publication
Date de publication:
Historique:
entrez:
12
3
2021
pubmed:
13
3
2021
medline:
16
10
2021
Statut:
ppublish
Résumé
Mycobacterium chimaera has been described in postoperative cardiovascular procedures in patients after an outbreak of contaminated 3T heater-cooler units. Immune reconstitution inflammatory syndrome (IRIS) has been mostly reported in immunocompromised patients, especially HIV after starting therapy. Our case is a 52-year-old immunocompetent male who was diagnosed with M. chimaera mediastinitis a year after Type A dissection repair and was started on quadruple antimicrobial therapy. He clinically improved but 8 months into therapy he presented with a declining kidney function, pancytopenia, and hypercalcemia which after bone marrow and kidney biopsies were attributed to IRIS. Our patient's diagnosis spared him subsequent surgery. IRIS during the treatment of nontuberculous mycobacteria must be suspected even in immunocompetent patients as reaching the diagnosis is very helpful in preventing additional diagnostic and therapeutic measures.
Identifiants
pubmed: 33707377
pii: IntJMycobacteriol_2021_10_1_82_310513
doi: 10.4103/ijmy.ijmy_242_20
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
82-84Déclaration de conflit d'intérêts
None