Renal Dysfunction in Cirrhosis: Critical Care Management.
Acute kidney injury in cirrhosis
Dialysis in cirrhosis
Hepatorenal syndrome
Renal dysfunction in cirrhosis
Renal replacement therapy in cirrhosis
Volume overload in cirrhosis
Journal
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
ISSN: 0972-5229
Titre abrégé: Indian J Crit Care Med
Pays: India
ID NLM: 101208863
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
entrez:
12
3
2021
pubmed:
13
3
2021
medline:
13
3
2021
Statut:
ppublish
Résumé
Cirrhotic patients with manifestations of the end-stage liver disease have a high risk for developing renal dysfunction even with minor insults. The development of renal dysfunction increases the morbidity and mortality of these patients. Causes of renal dysfunction in cirrhotics can be due to hepatorenal syndrome (HRS) or acute kidney injury (AKI) resulting from prerenal, renal, and postrenal causes. Development of pretransplant renal dysfunction has been shown to affect post-liver transplantation outcomes. Early detection and aggressive strategies for the prevention of further progression of renal dysfunction seem to decrease the morbidity and improve survival in this group of patients. This article aims to outline the pathogenesis of renal dysfunction in cirrhosis, etiological factors, and evaluation of renal dysfunction, strategies for aggressive therapy for renal dysfunction, the indications of renal replacement therapy (RRT) in this group of patients, and the various modalities of RRT with their merits and demerits. A thorough understanding of the pathogenesis, early detection, and aggressive corrective measures for AKI can prevent further progression. In conclusion, a good knowledge of treatment modalities available for renal dysfunction in cirrhosis and institution of timely interventions can significantly improve survival in this group of patients. Development of renal dysfunction in cirrhotics increases the morbidity and mortality of these patients and results in poor outcomes after liver transplantation. Early detection and aggressive strategies for the prevention of further progression of renal dysfunction seem to decrease the morbidity and improve survival in this group of patients. Rajakumar A, Appuswamy E, Kaliamoorthy I, Rela M. Renal Dysfunction in Cirrhosis: Critical Care Management. Indian J Crit Care Med 2021;25(2):207-214.
Identifiants
pubmed: 33707901
doi: 10.5005/jp-journals-10071-23721
pmc: PMC7922436
doi:
Types de publication
Journal Article
Langues
eng
Pagination
207-214Informations de copyright
Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.
Déclaration de conflit d'intérêts
Source of support: Nil Conflict of interest: None
Références
Hepatology. 2013 Feb;57(2):753-62
pubmed: 22454364
J Am Coll Cardiol. 2005 Dec 6;46(11):2043-6
pubmed: 16325039
Hepatology. 2003 Feb;37(2):233-43
pubmed: 12540770
Biomed Res Int. 2013;2013:108951
pubmed: 23971020
Hepatology. 2007 Mar;45(3):797-805
pubmed: 17326206
BMC Gastroenterol. 2015 Nov 25;15:167
pubmed: 26606982
Gastroenterology. 2008 May;134(5):1352-9
pubmed: 18471512
J Am Soc Nephrol. 1994 Feb;4(8):1522-30
pubmed: 8025225
Lancet. 2003 Nov 29;362(9398):1819-27
pubmed: 14654322
Dig Dis Sci. 2008 Mar;53(3):830-5
pubmed: 17939047
J Hepatol. 2007 May;46(5):935-46
pubmed: 17391801
Int Urol Nephrol. 2011 Mar;43(1):175-84
pubmed: 20306131
J Am Coll Cardiol. 2007 Feb 13;49(6):675-83
pubmed: 17291932
J Hepatol. 2003 Jul;39(1):24-31
pubmed: 12821040
Crit Care. 2008;12(2):R34
pubmed: 18318896
Wien Klin Wochenschr. 1997 Feb 28;109(4):123-7
pubmed: 9076929
Kidney Int Suppl (2011). 2012 Mar;2(1):89-115
pubmed: 25018921
Clin J Am Soc Nephrol. 2008 May;3(3):869-75
pubmed: 18235146
Arch Intern Med. 1994 Jan 24;154(2):201-5
pubmed: 8285815
N Engl J Med. 1999 Aug 5;341(6):403-9
pubmed: 10432325
Curr Opin Pediatr. 2011 Apr;23(2):194-200
pubmed: 21252674
Am J Transplant. 2012 Nov;12(11):2901-8
pubmed: 22822723
Transplantation. 2016 Oct;100(10):2122-8
pubmed: 27479161
Hepatology. 1996 Jan;23(1):164-76
pubmed: 8550036
Transplantation. 1995 Feb 15;59(3):361-5
pubmed: 7871566
Am J Kidney Dis. 2011 Dec;58(6):928-38
pubmed: 21962618
Nephrol Dial Transplant. 1997 Jun;12(6):1212-7
pubmed: 9198053
N Engl J Med. 2000 May 25;342(21):1581-9
pubmed: 10824078
Hepatology. 2002 May;35(5):1179-85
pubmed: 11981768
J Hepatol. 2007 Oct;47(4):499-505
pubmed: 17560680
J Surg Res. 2011 Nov;171(1):e139-47
pubmed: 21920550
N Engl J Med. 2008 Jul 3;359(1):7-20
pubmed: 18492867
Semin Liver Dis. 2008 Feb;28(1):3-25
pubmed: 18293274
Gut. 2011 Mar;60(3):412-21
pubmed: 21193458
Intensive Care Med. 2005 Dec;31(12):1693-9
pubmed: 16244877
Am J Gastroenterol. 2001 Jul;96(7):2206-10
pubmed: 11467654
Anesthesiology. 2006 Sep;105(3):485-91
pubmed: 16931980
J Gastroenterol Hepatol. 2010 May;25(5):880-5
pubmed: 20074149
N Engl J Med. 2009 Sep 24;361(13):1279-90
pubmed: 19776409
Nephrol Dial Transplant. 2011 Jul;26(7):2169-75
pubmed: 21075821
J Hepatol. 2011 Dec;55(6):1241-8
pubmed: 21703199
Hepatology. 2005 Aug;42(2):439-47
pubmed: 15977202
Am J Kidney Dis. 2001 Mar;37(3):457-66
pubmed: 11228168
J Crit Care. 2012 Dec;27(6):744.e7-15
pubmed: 23102533
Am J Gastroenterol. 2008 Jul;103(7):1689-97
pubmed: 18557715
Kidney Int Suppl. 1993 Jun;41:S245-51
pubmed: 8320931
N Engl J Med. 2009 Oct 22;361(17):1627-38
pubmed: 19846848
Hepatology. 1997 Jun;25(6):1328-33
pubmed: 9185747
Crit Care Med. 2008 Feb;36(2):610-7
pubmed: 18216610
N Engl J Med. 1998 Aug 20;339(8):533-41
pubmed: 9709047
Liver Int. 2009 Mar;29(3):415-9
pubmed: 18803587
J Hepatol. 2006 Jan;44(1):217-31
pubmed: 16298014
Hepatology. 1988 Sep-Oct;8(5):1151-7
pubmed: 2971015
Am J Gastroenterol. 2004 Apr;99(4):619-22
pubmed: 15089891
Int J Artif Organs. 2007 Dec;30(12):1083-9
pubmed: 18203070
J Hepatol. 2012 Apr;56(4):810-8
pubmed: 22173162
Crit Care. 2007;11(2):R31
pubmed: 17331245
Am J Transplant. 2006 Nov;6(11):2651-9
pubmed: 16939515
Gastroenterology. 2008 May;134(5):1360-8
pubmed: 18471513
Crit Care. 2008;12(3):R74
pubmed: 18533029
Hepatology. 2014 Aug;60(2):622-32
pubmed: 24375576
Intensive Care Med. 1987;13(6):401-4
pubmed: 3668074
Gastroenterology. 2002 Jan;122(1):85-93
pubmed: 11781284
N Engl J Med. 2016 Jul 14;375(2):122-33
pubmed: 27181456
Int J Prev Med. 2012 Nov;3(11):764-9
pubmed: 23189227
Blood Purif. 2004;22(1):164-74
pubmed: 14732825
J Hepatol. 2010 Apr;52(4):605-13
pubmed: 20185192
Intensive Care Med. 2007 May;33(5):830-835
pubmed: 17384931
Hepatology. 2015 Aug;62(2):567-74
pubmed: 25644760
Crit Care. 2015 Sep 29;19:349
pubmed: 26415638
Med Clin North Am. 2008 Jul;92(4):813-37, viii-ix
pubmed: 18570944
Can J Gastroenterol. 2009 Jun;23(6):441-5
pubmed: 19543577
Am J Kidney Dis. 2002 Aug;40(2):221-6
pubmed: 12148093
Gut. 2007 Sep;56(9):1310-8
pubmed: 17389705
Lancet. 2005 Apr 2-8;365(9466):1231-8
pubmed: 15811456
Gut. 2002 Jan;50(1):106-10
pubmed: 11772976
Transplantation. 2009 May 27;87(10):1514-9
pubmed: 19461488
Int J Artif Organs. 2003 Jun;26(6):477-83
pubmed: 12866653
Crit Care Med. 2003 Oct;31(10):2450-5
pubmed: 14530750
J Hepatol. 2016 Mar;64(3):717-35
pubmed: 26519602
Turk J Gastroenterol. 2016 Mar;27(2):173-9
pubmed: 27015622
Intensive Care Med. 2008 Jan;34(1):17-60
pubmed: 18058085
Am J Nephrol. 2005 May-Jun;25(3):282-9
pubmed: 15961948
J Hepatol. 2012 Jun;56(6):1293-8
pubmed: 22322237
Crit Care. 2000;4(6):339-45
pubmed: 11123877
BMC Nephrol. 2010 Nov 25;11:32
pubmed: 21106112
Ann Pharmacother. 2009 Apr;43(4):692-9
pubmed: 19299324
Gastroenterology. 1993 Jul;105(1):229-36
pubmed: 8514039
N Engl J Med. 2002 Sep 19;347(12):895-902
pubmed: 12239258
Kidney Int. 2000 Oct;58(4):1765-72
pubmed: 11012911
Hepatology. 1994 Dec;20(6):1495-501
pubmed: 7982650
Hepatology. 2002 Aug;36(2):374-80
pubmed: 12143045
Kidney Int Suppl. 2008 Apr;(108):S87-93
pubmed: 18379555
Int J Hepatol. 2015;2015:309042
pubmed: 26550493
PLoS One. 2014 Sep 09;9(9):e107466
pubmed: 25203311
J Card Fail. 2010 Apr;16(4):277-84
pubmed: 20350693
J Nephrol. 2003 Jul-Aug;16(4):566-71
pubmed: 14696760
J Hepatol. 2009 Sep;51(3):504-9
pubmed: 19615775
Hepatology. 2016 Mar;63(3):983-92
pubmed: 26659927
Lancet. 2012 Aug 25;380(9843):756-66
pubmed: 22617274
Adv Perit Dial. 2010;26:82-7
pubmed: 21348386
Am J Cardiovasc Drugs. 2013 Oct;13(5):365-73
pubmed: 23801482
Hepatology. 2010 Feb;51(2):576-84
pubmed: 19885875
Liver Transpl. 2012 Oct;18(10):1237-44
pubmed: 22714872
Kidney Int. 2009 Aug;76(4):422-7
pubmed: 19436332
Gastroenterology. 2008 Jan;134(1):111-9
pubmed: 18166350
Crit Care Med. 2008 Nov;36(11):3024-9
pubmed: 18824904