Management of Metastatic Spine and Hip Alveolar Soft Part Sarcoma: Case Report and Review of Literature.
Alveolar soft part sarcoma
hip
metastasis
spine
surgery
Journal
Asian journal of neurosurgery
ISSN: 1793-5482
Titre abrégé: Asian J Neurosurg
Pays: India
ID NLM: 101564712
Informations de publication
Date de publication:
Historique:
received:
12
06
2020
revised:
09
08
2020
accepted:
24
09
2020
entrez:
12
3
2021
pubmed:
13
3
2021
medline:
13
3
2021
Statut:
epublish
Résumé
Alveolar soft part sarcoma (ASPS) is a rare soft tissue tumor. Primary or metastatic involvement of the spine is unusual in ASPS. In most case, it is refractory to chemotherapy and radiation. Surgical resection is the most effective intervention. We report the case of a 38-year-old female having ASPS along with metastatic spine and hip involvement treated surgically as a single-stage operation, which is the first of its kind approach to our knowledge. We present the case of a 38-year-old female with simultaneous L4 pathological fracture with symptomatic lumbar canal stenosis without focal neurology and pathological fracture of neck of femur of left hip, secondary to metastatic ASPS. Since both conditions were contributing equally to her disability and demanded early intervention, they were treated simultaneously with intralesional excision of the tumor and posterior stabilization of the spine and left hip proximal femur resection and replaced it with proximal femur endoprosthesis as a single-stage operation. Postoperatively, she had significant relief of radiculopathy and left hip pain. She was mobilized out of bed on the postoperative day 1 and was discharged from hospital on the postoperative day 6. She was given chemotherapy drug sunitib postoperative. At her last follow-up, 20 months' postoperative, she was asymptomatic and was independent in terms of activities of daily living. Metastatic ASPS of the spine and hip is a rare clinical entity. Simultaneous surgical treatment of the spine and hip pathology is technically demanding. If the conditions demands, as in our case, both of them can be managed safely in a single-stage with good midterm outcome.
Identifiants
pubmed: 33708679
doi: 10.4103/ajns.AJNS_290_20
pii: AJNS-15-1011
pmc: PMC7869264
doi:
Types de publication
Case Reports
Langues
eng
Pagination
1011-1015Informations de copyright
Copyright: © 2020 Asian Journal of Neurosurgery.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
Cancer. 1987 Jul 1;60(1):66-73
pubmed: 2438029
J Neurooncol. 2012 May;107(3):551-7
pubmed: 22246201
Spine (Phila Pa 1976). 2010 Oct 15;35(22):E1221-9
pubmed: 20562730
JAMA. 1966 Dec 5;198(10):1047-51
pubmed: 5953380
Cancer. 2001 Feb 1;91(3):585-91
pubmed: 11169942
Ann Oncol. 2000 Nov;11(11):1445-9
pubmed: 11142485
Skeletal Radiol. 2009 Aug;38(8):825-9
pubmed: 19347336
J Pediatr Hematol Oncol. 2008 Jan;30(1):46-52
pubmed: 18176180
Skeletal Radiol. 1995 May;24(4):267-70
pubmed: 7644939
Clin Cancer Res. 2009 Feb 1;15(3):1096-104
pubmed: 19188185
Fetal Pediatr Pathol. 2008;27(1):31-40
pubmed: 18568987
J Pediatr Neurosci. 2012 Jan;7(1):36-9
pubmed: 22837776
Neurosurgery. 2009 Feb;64(2 Suppl):A54-9
pubmed: 19165074
Ann Oncol. 2011 Jul;22(7):1682-1690
pubmed: 21242589
Int J Radiat Oncol Biol Phys. 2011 Mar 15;79(4):965-76
pubmed: 21277118
Spine (Phila Pa 1976). 2009 Oct 15;34(22 Suppl):S101-7
pubmed: 19829269
Int J Radiat Oncol Biol Phys. 2014 Apr 1;88(5):1085-91
pubmed: 24661662
J Clin Pathol. 2006 Nov;59(11):1127-32
pubmed: 17071801
Childs Nerv Syst. 2014 Feb;30(2):345-50
pubmed: 23793948
Spine (Phila Pa 1976). 2005 Oct 1;30(19):2186-91
pubmed: 16205345
J Bone Joint Surg Br. 2005 Dec;87(12):1653-7
pubmed: 16326880
Ann Surg Oncol. 2010 Dec;17(12):3229-33
pubmed: 20593242