Multimodal imaging in infectious and noninfectious intermediate, posterior and panuveitis.
Choroid
/ diagnostic imaging
Fluorescein Angiography
Humans
Multimodal Imaging
Optical Imaging
Panuveitis
/ diagnostic imaging
Retina
/ diagnostic imaging
Retinal Vessels
/ diagnostic imaging
Tomography, Optical Coherence
Uveitis, Intermediate
/ diagnostic imaging
Uveitis, Posterior
/ diagnostic imaging
Vitreous Body
/ diagnostic imaging
Journal
Current opinion in ophthalmology
ISSN: 1531-7021
Titre abrégé: Curr Opin Ophthalmol
Pays: United States
ID NLM: 9011108
Informations de publication
Date de publication:
01 May 2021
01 May 2021
Historique:
pubmed:
13
3
2021
medline:
22
5
2021
entrez:
12
3
2021
Statut:
ppublish
Résumé
Given the heterogeneity of uveitis, markers of inflammation vary from patient to patient. Multimodal imaging has proven itself to be critical for accurate evaluation for disease activity and treatment response in uveitis. Ultra-widefield (UWF) fluorescein angiography and autofluorescence (AF) as well as optical coherence tomography angiography (OCTA) have provided insights into disease pathogenesis and monitoring not previously appreciated. In addition to structural retinal imaging, OCT can be used to assess the choroid, the posterior cortical vitreous and the retinal vasculature in eyes with uveitis. Multimodal ocular imaging in eyes with uveitis is critical for disease diagnosis and assessing response to treatment. UWF fluorescein angiography can detect retinal vasculitis even in the absence of overt vascular sheathing. UWF AF can help detect more chorioretinal lesions than clinically visible. OCT can be used to assess the posterior cortical vitreous, retina, large retinal vessels and choroid in uveitis. The use of multimodal imaging will likely be needed to determine clinical trial endpoints in studies evaluating therapeutics for uveitis.
Identifiants
pubmed: 33710009
doi: 10.1097/ICU.0000000000000762
pii: 00055735-202105000-00002
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
169-182Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
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