The Effect of Various Supportive Housing Models on ART Adherence Among Persons Living With HIV in Supportive Housing.


Journal

Medical care
ISSN: 1537-1948
Titre abrégé: Med Care
Pays: United States
ID NLM: 0230027

Informations de publication

Date de publication:
01 04 2021
Historique:
entrez: 12 3 2021
pubmed: 13 3 2021
medline: 16 11 2021
Statut: ppublish

Résumé

Providing permanent supportive housing to chronically homeless persons living with human immunodeficiency virus (PLH) contributes to improved human immunodeficiency virus (HIV) outcomes, including adherence to antiretroviral therapy (ART). This study seeks to understand whether certain components of housing, namely intensity of case management and specialized HIV housing programs, affects ART adherence for PLH in supportive housing. From 2015 to 2019 we conducted quantitative assessments with 157 PLH in supportive housing at baseline, 6-, 12-, and 18-month postbaseline to identify factors associated with ART adherence. General Estimating Equations for repeated measures were performed to assess bivariate and multivariate measures. Two thirds of PLH in supportive housing reported 95% or greater adherence to ART. Multivariate analyses indicate that neither intensity of case management services nor specialized housing for PLH were associated with greater ART adherence. Greater time since diagnosis was positively associated with ART adherence. Greater depressive symptoms and African American race were negatively associated with ART adherence. Study findings reveal that although prior research has established the importance of receipt of housing for homeless PLH, the type or intensity of case management services associated with that housing may not be as important as simply being housed. Our results highlight the importance of considering mental health and more recent HIV diagnosis when developing treatment and case management plans to enhance residents' ART adherence.

Sections du résumé

BACKGROUND
Providing permanent supportive housing to chronically homeless persons living with human immunodeficiency virus (PLH) contributes to improved human immunodeficiency virus (HIV) outcomes, including adherence to antiretroviral therapy (ART). This study seeks to understand whether certain components of housing, namely intensity of case management and specialized HIV housing programs, affects ART adherence for PLH in supportive housing.
METHODS
From 2015 to 2019 we conducted quantitative assessments with 157 PLH in supportive housing at baseline, 6-, 12-, and 18-month postbaseline to identify factors associated with ART adherence. General Estimating Equations for repeated measures were performed to assess bivariate and multivariate measures.
RESULTS
Two thirds of PLH in supportive housing reported 95% or greater adherence to ART. Multivariate analyses indicate that neither intensity of case management services nor specialized housing for PLH were associated with greater ART adherence. Greater time since diagnosis was positively associated with ART adherence. Greater depressive symptoms and African American race were negatively associated with ART adherence.
CONCLUSIONS
Study findings reveal that although prior research has established the importance of receipt of housing for homeless PLH, the type or intensity of case management services associated with that housing may not be as important as simply being housed. Our results highlight the importance of considering mental health and more recent HIV diagnosis when developing treatment and case management plans to enhance residents' ART adherence.

Identifiants

pubmed: 33710084
doi: 10.1097/MLR.0000000000001336
pii: 00005650-202104001-00008
pmc: PMC7958970
mid: NIHMS1578113
doi:

Substances chimiques

Anti-Retroviral Agents 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

S124-S131

Subventions

Organisme : NIMH NIH HHS
ID : K01 MH112412
Pays : United States
Organisme : NIMH NIH HHS
ID : P30 MH052776
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA038085
Pays : United States

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

United States Department of Housing and Urban Development. HUD 2018 Continuum of Care Homeless Assistance Programs Homeless Populations and Subpopulations. Washington DC: US Department of Housing and Urban Development; 2018.
Aidala AA, Wilson MG, Shubert V, et al. Housing status, medical care, and health outcomes among people living with HIV/AIDS: a systematic review. Am J Public Health. 2016;106:e1–e23.
Aidala A, Lee G, Abramson DM, et al. Housing need, housing assistance, and connection to HIV medical care. AIDS Behav. 2007;11(suppl):101–115.
Ingle SM, May MT, Gill MJ, et al. Impact of risk factors for specific causes of death in the first and subsequent years of antiretroviral therapy among HIV-infected patients. Clin Infect Dis. 2014;59:287–297.
Kidder DP, Wolitski RJ, Royal S, et al. Access to housing as a structural intervention for homeless and unstably housed people living with HIV: rationale, methods, and implementation of the housing and health study. AIDS Behav. 2007;11(suppl):149–161.
Wong MD, Cunningham WE, Shapiro MF, et al. Disparities in HIV treatment and physician attitudes about delaying protease inhibitors for nonadherent patients. J Gen Intern Med. 2004;19:366–374.
Kidder DP, Wolitski RJ, Campsmith ML, et al. Health status, health care use, medication use, and medication adherence among homeless and housed people living with HIV/AIDS. Am J Public Health. 2007;97:2238–2245.
Knowlton A, Arnsten J, Eldred L, et al. Individual, interpersonal, and structural correlates of effective HAART use among urban active injection drug users. J Acquir Immune Defic Syndr. 2006;41:486–492.
Thompson MA, Mugavero MJ, Amico KR, et al. Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an International Association of Physicians in AIDS Care panel. Ann Intern Med. 2012;156:817–833.
Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365:493–505.
Bezabhe WM, Chalmers L, Bereznicki LR, et al. Adherence to antiretroviral therapy and virologic failure. Medicine (Baltimore). 2016;95:e3361.
National Academies of Science Engineering and Medicine. Permanent Supportive Housing: Evaluating the Evidence for Improving Health Outcomes Among People Experiencing Chronic Homelessness. Washington, DC: The National Academies Press; 2018.
Rog DJ. The evidence on supported housing. Psychiatr Rehabil J. 2004;27:334.
Wong Y-LI, Hadley TR, Culhane DP, et al. Predicting staying in or leaving permanent supportive housing that serves homeless people with serious mental illness; 2006. Available at: http://repository.upenn.edu/spp_papers/111 . Accessed March 1, 2020.
The United States Department of Housing and Urban Development. Housing First in Permanent Supportive Housing Brief. Washington, DC: US Department of Housing and Urban Development; 2014.
Srebnik D, Connor T, Sylla L. A pilot study of the impact of Housing First–supported housing for intensive users of medical hospitalization and sobering services. Am J Public Health. 2013;103:316–321.
Lipton FR, Siegel C, Hannigan A, et al. Tenure in supportive housing for homeless persons with severe mental illness. Psychiatr Serv. 2000;51:479–486.
Rog DJ, Marshall T, Dougherty RH, et al. Permanent supportive housing: assessing the evidence. Psychiatr Serv. 2014;65:287–294.
Caton CLM, Wilkins C, Anderson J. People Who Experience Long-Term Homelessness: Characteristics and Interventions. Washington, DC: National Symposium on Homelessness Research; 2007.
Quinn K, Dickson-Gomez J, Nowicki K, et al. Supportive housing for chronically homeless individuals: challenges and opportunities for providers in Chicago, USA. Health Soc Care Community. 2018;26:e31–e38.
Dickson-Gomez J, Quinn K, Bendixen AV, et al. Identifying variability in permanent supportive housing: a comparative effectiveness approach to measuring health outcomes. Am J Orthopsychiatry. 2017;87:414.
Buchanan D, Kee R, Sadowski LS, et al. The health impact of supportive housing for HIV-positive homeless patients: a randomized controlled trial. Am J Public Health. 2009;99(suppl 3):S675–S680.
Hall G, Singh T, Lim SW. Supportive housing promotes AIDS-free survival for chronically homeless HIV positive persons with behavioral health conditions. AIDS Behav. 2019;23:776–783.
Towe VL, Wiewel EW, Zhong Y, et al. A randomized controlled trial of a rapid re-housing intervention for homeless persons living with HIV/AIDS: impact on housing and HIV medical outcomes. AIDS Behav. 2019;23:2315–2325.
Amico KR, Fisher WA, Cornman DH, et al. Visual analog scale of ART adherence: Association with 3-day self-report and adherence barriers. J Acquir Immune Defic Syndr. 2006;42:455–459.
Kalichman SC, Amaral CM, Swetzes C, et al. A simple single-item rating scale to measure medication adherence: further evidence for convergent validity. J Int Assoc Physicians AIDS Care. 2009;8:367–374.
Cohen MS, Chen YQ, McCauley M, et al. Antiretroviral therapy for the prevention of HIV-1 transmission. N Engl J Med. 2016;375:830–839.
Paterson DL, Swindells S, Mohr J, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133:21–30.
Tsemberis S, Gulcur L, Nakae M. Housing first, consumer choice, and harm reduction for homeless individuals with a dual diagnosis. Am J Public Health. 2004;94:651–656.
Jones DJ, Forehand R, Brody G, et al. Psychosocial adjustment of African American children in single‐mother families: a test of three risk models. J Marriage Fam. 2002;64:105–115.
Cunningham WE, Hays RD, Williams KW, et al. Access to medical care and health-related quality of life for low-income persons with symptomatic human immunodeficiency virus. Med Care. 1995;33:739–754.
Cunningham WE, Andersen RM, Katz MH, et al. The impact of competing subsistence needs and barriers on access to medical care for persons with human immunodeficiency virus receiving care in the United States. Med Care. 1999;37:1270–1281.
Andresen EM, Malmgren JA, Carter WB, et al. Screening for depression in well older adults: evaluation of a short form of the CES-D. Am J Prev Med. 2018;10:77–84.
Spitzer RL, Kroenke K, Williams JBW, et al. A brief measure for assessing generalized anxiety disorder: The GAD-7. Arch Intern Med. 2006;166:1092–1097.
Hays RD, Cunningham WE, Sherbourne CD, et al. Health-related quality of life in patients with human immunodeficiency virus infection in the United States: results from the HIV cost and services utilization study. Am J Med. 2000;108:714–722.
Fleishman JA, Sherbourne CD, Crystal S, et al. Coping, conflictual social interactions, social support, and mood among HIV-infected persons. Am J Community Psychol. 2000;28:421–453.
Lin D, Zhang CY, He ZK, et al. How does hard-to-reach status affect antiretroviral therapy adherence in the HIV-infected population? Results from a meta-analysis of observational studies. BMC Public Health. 2019;19:789.
Quinn K, Young S, Thomas D, et al. The role of supportive housing for HIV-positive mothers and their children. J Soc Serv Res. 2015;41:642–658.
Dickson-Gomez J, McAuliffe T, Obidoa C, et al. The relationship between housing subsidies and supportive housing on neighborhood distress and housing satisfaction: does drug use make a difference? Subst Abuse Treat Prev Policy. 2016;11:20.
Stergiopoulos V, Hwang SW, Gozdzik A, et al. Effect of scattered-site housing using rent supplements and intensive case management on housing stability among homeless adults with mental illness: a randomized trial. JAMA. 2015;313:905–915.
Sadowski LS, Kee RA, VanderWeele TJ, et al. Effect of a housing and case management program on emergency department visits and hospitalizations among chronically ill homeless adults: a randomized trial. JAMA. 2009;301:1771–1778.
Katz MH, Cunningham WE, Mor V, et al. Prevalence and predictors of unmet need for supportive services among HIV-infected persons: impact of case management. Med Care. 2000;38:58–69.
Smelson DA, Zaykowski H, Guevermont N, et al. Integrating permanent supportive housing and co-occurring disorders treatment for individuals who are homeless. J Dual Diagn. 2016;12:193–201.
Langebeek N, Gisolf EH, Reiss P, et al. Predictors and correlates of adherence to combination antiretroviral therapy (ART) for chronic HIV infection: a meta-analysis. BMC Med. 2014;12:142.
Bianco JA, Heckman TG, Sutton M, et al. Predicting adherence to antiretroviral therapy in HIV-infected older adults: The moderating role of gender. AIDS Behav. 2011;15:1437–1446.
Dale SK, Bogart LM, Wagner GJ, et al. Medical mistrust is related to lower longitudinal medication adherence among African-American males with HIV. J Health Psychol. 2016;21:1311–1321.
Bogart WG, Galvan FH, Banks D. Conspiracy beliefs about HIV are related to antiretroviral treatment nonadherence among african american men with HIV. J Acquir Immune Defic Syndr. 2010;53:648–655.
Kelso GA, Cohen MH, Weber KM, et al. Critical consciousness, racial and gender discrimination, and HIV disease markers in African American women with HIV. AIDS Behav. 2014;18:1237–1246.
Wolitski RJ, Pals SL, Kidder DP, et al. The effects of HIV stigma on health, disclosure of HIV status, and risk behavior of homeless and unstably housed persons living with HIV. AIDS Behav. 2009;13:1222–1232.
Wagner GJ, Bogart LM, Galvan FH, et al. Discrimination as a key mediator of the relationship between posttraumatic stress and HIV treatment adherence among African American men. J Behav Med. 2012;35:8–18.

Auteurs

Katherine G Quinn (KG)

Department of Psychiatry and Behavioral Medicine, Center for AIDS Intervention Research.

Wayne DiFranceisco (W)

Department of Psychiatry and Behavioral Medicine, Center for AIDS Intervention Research.

Antoinette Spector (A)

Institute for Health and Equity, Medical College of Wisconsin, Milwaukee, WI.

Art Bendixen (A)

The Center for Housing and Health.

Amanda Peters (A)

The AIDS Foundation of Chicago, Chicago, IL.

Julia Dickson-Gomez (J)

Department of Psychiatry and Behavioral Medicine, Center for AIDS Intervention Research.
Institute for Health and Equity, Medical College of Wisconsin, Milwaukee, WI.

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