Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID-19.

Adenosine / analogs & derivatives Adenosine Monophosphate / analogs & derivatives Alanine / analogs & derivatives Blood Chemical Analysis COVID-19 / blood Chromatography, Liquid Combined Modality Therapy Furans / blood Hemoperfusion / adverse effects Humans Pyrroles / blood Tandem Mass Spectrometry Triazines / blood
COVID-19 SARS-CoV-2 cytokine hemoadsorption remdesivir

Journal

Pharmacology research & perspectives
ISSN: 2052-1707
Titre abrégé: Pharmacol Res Perspect
Pays: United States
ID NLM: 101626369

Informations de publication

Date de publication:
04 2021
Historique:
received: 20 01 2021
revised: 27 01 2021
accepted: 28 01 2021
entrez: 12 3 2021
pubmed: 13 3 2021
medline: 26 3 2021
Statut: ppublish

Résumé

Both antiviral treatment with remdesivir and hemoadsorption using a CytoSorb

Identifiants

DOI: 10.1002/prp2.743 PMID: 33710753 PMC: PMC7953359
pubmed: 33710753
doi: 10.1002/prp2.743
pmc: PMC7953359
doi:

Substances chimiques

Furans 0
Pyrroles 0
Triazines 0
GS-441524 1BQK176DT6
remdesivir 3QKI37EEHE
Adenosine Monophosphate 415SHH325A
Adenosine K72T3FS567
Alanine OF5P57N2ZX

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e00743

Informations de copyright

© 2021 The Authors. Pharmacology Research & Perspectives published by British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics and John Wiley & Sons Ltd.

Références

Drugs R D. 2020 Sep;20(3):217-223
pubmed: 32415538
Blood Purif. 2002;20(4):380-8
pubmed: 12169849
Intensive Care Med. 2019 Feb;45(2):236-239
pubmed: 30446798
Crit Care. 2020 Jul 14;24(1):435
pubmed: 32664996
Clin Transl Sci. 2020 Sep;13(5):896-906
pubmed: 32589775
Pharmacol Res Perspect. 2021 Feb;9(1):e00705
pubmed: 33421347
Intensive Care Med Exp. 2020 Jun 15;8(1):21
pubmed: 32542550
Cell Rep. 2020 Jul 21;32(3):107940
pubmed: 32668216
JACC Basic Transl Sci. 2017 Apr 24;2(2):135-145
pubmed: 30167561
Clin Chem Lab Med. 2020 Jun 22;58(9):1461-1468
pubmed: 32573468
Int J Cardiol. 2019 Oct 15;293:73-75
pubmed: 31296393
Blood Purif. 2018;45(1-3):126-128
pubmed: 29402788

Auteurs

Paul Biever (P)

Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Medicine II (Division of Infectious Diseases), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Dawid L Staudacher (DL)

Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Michaela J Sommer (MJ)

Institute of Forensic Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Hermann Staudinger Graduate School, University of Freiburg, Freiburg, Germany.

Hannah Triebel (H)

Institute of Forensic Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Merja A Neukamm (MA)

Institute of Forensic Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Christoph Bode (C)

Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Alexander Supady (A)

Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany.

Achim Lother (A)

Heart Center Freiburg University, Department of Cardiology and Angiology I, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
ORCID: 0000-0001-9107-5558

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Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléosides › Ribonucléosides › Adénosine › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › AMP › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Alanine › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Tests de chimie clinique › Analyse chimique du sang › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Chromatographie › Chromatographie en phase liquide › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Thérapeutique › Association thérapeutique › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Furanes › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Procédures de chirurgie opératoire › Circulation extracorporelle › Hémoperfusion › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Pyrroles › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse en tandem › Hemoadsorption eliminates remdesivir from the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Triazines › Hemoadsorption eliminates remdesivir from the...