Continuous renal replacement therapy and extended indications.


Journal

Seminars in dialysis
ISSN: 1525-139X
Titre abrégé: Semin Dial
Pays: United States
ID NLM: 8911629

Informations de publication

Date de publication:
11 2021
Historique:
revised: 02 02 2021
received: 26 11 2020
accepted: 08 02 2021
pubmed: 13 3 2021
medline: 15 3 2022
entrez: 12 3 2021
Statut: ppublish

Résumé

Extracorporeal blood purification (EBP) techniques provide support for critically ill patients with single or multiple organ dysfunction. Continuous renal replacement therapy (CRRT) is the modality of choice for kidney support for those patients and orchestrates the interactions between the different artificial organ support systems. Intensive care teams should be familiar with the concept of sequential extracorporeal therapy and plan on how to incorporate new treatment modalities into their daily practices. Importantly, scientific evidence should guide the decision-making process at the bedside and provide robust arguments to justify the costs of implementing new EBP treatments. In this narrative review, we explore the extended indications for CRRT as an adjunctive treatment to provide support for the heart, lung, liver, and immune system. We detail practicalities on how to run the treatments and how to tackle the most frequent complications regarding each of the therapies, whether applied alone or integrated. The physicochemical processes and technologies involved at the molecular level encompassing the interactions between the molecules, membranes, and resins are spotlighted. A clinical case will illustrate the timing for the initiation, maintenance, and discontinuation of EBP techniques.

Identifiants

pubmed: 33711166
doi: 10.1111/sdi.12963
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

550-560

Informations de copyright

© 2021 Wiley Periodicals LLC.

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Auteurs

Claudio Ronco (C)

Department of Medicine (DIMED), University of Padova, Padova, Italy.
Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza, Italy.
National Academy of Medicine, Young Leadership Physicians Program, Rio de Janeiro, Brazil.

Thiago Reis (T)

Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza, Italy.
Department of Nephrology, Clínica de Doenças Renais de Brasília, Molecular Pharmacology Laboratory, University of Brasília, Brasilia, Brazil.

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