Maternal and neonatal outcomes in planned versus emergency cesarean delivery for placenta accreta spectrum: A multinational database study.


Journal

Acta obstetricia et gynecologica Scandinavica
ISSN: 1600-0412
Titre abrégé: Acta Obstet Gynecol Scand
Pays: United States
ID NLM: 0370343

Informations de publication

Date de publication:
03 2021
Historique:
revised: 30 01 2021
received: 17 10 2020
accepted: 05 02 2021
pubmed: 14 3 2021
medline: 23 4 2021
entrez: 13 3 2021
Statut: ppublish

Résumé

Placenta accreta spectrum (PAS) is a condition often resulting in severe maternal morbidity. Scheduled delivery by an experienced team has been shown to improve maternal outcomes; however, the benefits must be weighed against the risk of iatrogenic prematurity. The aim of this study is to investigate the rates of emergency delivery seen for antenatally suspected PAS and compare the resulting outcomes in the 15 referral centers of the International Society for PAS (IS-PAS). Fifteen centers provided cases between 2008 and 2019. The women included were divided into two groups according to whether they had a planned or an emergency cesarean delivery. Delivery was defined as "planned" when performed at a time and date to suit the team. All the remaining cases were classified as "emergency". Maternal characteristics and neonatal outcomes were compared between the two groups according to gestation at delivery. In all, 356 women were included. Of these, 239 (67%) underwent a planned delivery and 117 (33%) an emergency delivery. Vaginal bleeding was the indication for emergency delivery in 41 of the 117 women (41%). There were no significant differences in terms of blood loss, transfusion rates or major maternal morbidity between planned and emergency deliveries. However, the rate of maternal intensive therapy unit admission was increased with emergency delivery (45% vs 33%, P = .02). Antepartum hemorrhage was the only independent predictor of emergency delivery (aOR: 4.3, 95% confidence interval 2.4-7.7). Emergency delivery due to vaginal bleeding was more frequent with false-positive cases (antenatally suspected but not confirmed as PAS at delivery) and the milder grades of PAS (accreta/increta). The rate of infants experiencing any major neonatal morbidity was 25% at 34 Emergency delivery in centers of excellence did not increase blood loss, transfusion rates or maternal morbidity. The single greatest risk factor for emergency delivery was antenatal hemorrhage. When adequate expertise and resources are available, to defer delivery in women with no significant antenatal bleeding and no risk factors for pre-term birth until >36

Identifiants

pubmed: 33713033
doi: 10.1111/aogs.14120
doi:

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

41-49

Investigateurs

Pavel Calda (P)
Fredric Chantraine (F)
Johannes J Duvekot (JJ)
Karin A Fox (KA)
Lene Gronbeck (L)
Wolfgang Henrich (W)
Pasquale Martinelli (P)
Jorma Paavonen (J)
Philippe Petit (P)
Marcus Rijken (M)
Mariola Ropacka (M)
Minna Tikkanen (M)
Alexander Weichert (A)
Katharina Weizsäcker (K)

Informations de copyright

© 2021 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).

Références

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Auteurs

Maddalena Morlando (M)

Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Department of Woman, Child and of General and Specialized Surgery, University "Luigi Vanvitelli", Naples, Italy.

Alexander Schwickert (A)

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Obstetrics, Berlin, Germany.

Vedran Stefanovic (V)

Department of Obstetrics and Gynecology, Fetomaternal Medical Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Mina M Gziri (MM)

Department of Obstetrics, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

Petra Pateisky (P)

Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, Vienna, Austria.

Kinga M Chalubinski (KM)

Department of Obstetrics and Gynecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, Vienna, Austria.

Andreas Nonnenmacher (A)

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Obstetrics, Berlin, Germany.

Olivier Morel (O)

Women's Division, Nancy Regional and University Hospital Center (CHRU), Université de Lorraine, Nancy, France.
Diagnosis and International Adaptive Imaging (IADI), Inserm, Université de Lorraine, Nancy, France.

Thorsten Braun (T)

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Obstetrics, Berlin, Germany.
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of 'Experimental Obstetrics', Berlin, Germany.

Charline Bertholdt (C)

Women's Division, Nancy Regional and University Hospital Center (CHRU), Université de Lorraine, Nancy, France.
Diagnosis and International Adaptive Imaging (IADI), Inserm, Université de Lorraine, Nancy, France.

Heleen J Van Beekhuizen (HJ)

Department of Gynecological Oncology, Erasmus MC Cancer center, Rotterdam, the Netherlands.

Sally L Collins (SL)

Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Fetal Medicine Unit, John Radcliffe Hospital, Oxford, UK.

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