Cryptococcus Infection in Captive Callitrichids in the United Kingdom.


Journal

Journal of comparative pathology
ISSN: 1532-3129
Titre abrégé: J Comp Pathol
Pays: England
ID NLM: 0102444

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 30 05 2020
revised: 08 11 2020
accepted: 06 12 2020
entrez: 14 3 2021
pubmed: 15 3 2021
medline: 9 11 2021
Statut: ppublish

Résumé

Cryptococcosis is widely reported in North America and Australia but considered rare in the UK. Disease is mainly caused by Cryptococcus neoformans and Cryptococcus gattii and affects animals and humans. Cases of cryptococcosis have been described in non-human primates, including a few in the Callitrichidae family. Six captive callitrichids from five zoological facilities in the UK were diagnosed with cryptococcosis on post-mortem examination over a 13-year period. Histological examination revealed intralesional yeast bodies consistent with Cryptococcus spp in lung, brain, lymph nodes, larynx, salivary gland and ears. C. neoformans was confirmed in two cases by culture and by culture and polymerase chain reaction (28S rRNA gene), respectively. This case series is the first report of Cryptococcus spp in captive callitrichids in the UK and reinforces the need to include this fungal disease in the differential diagnosis of sick callitrichids in zoo settings.

Identifiants

pubmed: 33714426
pii: S0021-9975(20)30159-6
doi: 10.1016/j.jcpa.2020.12.001
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-8

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Stephanie M Mota (SM)

Royal Zoological Society of Scotland, Edinburgh Zoo, Edinburgh, UK.

Mark F Stidworthy (MF)

International Zoo Veterinary Group, Keighley, UK.

Amanda Guthrie (A)

Zoological Society of London, London Zoo, Regent's Park, London, UK.

Simon Spiro (S)

Zoological Society of London, London Zoo, Regent's Park, London, UK.

Daniela Denk (D)

International Zoo Veterinary Group, Keighley, UK. Electronic address: danieladenk@gmail.com.

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Classifications MeSH