Focal Spinal Nondisjunction in Primary Neurulation : Limited Dorsal Myeloschisis and Congenital Spinal Dermal Sinus Tract.
Dermoid
Dysraphism
Focal spinal nondisjunctional disorders
Limited dorsal myeloschisis
Nondisjunction
Spinal dermal sinus tract
Journal
Journal of Korean Neurosurgical Society
ISSN: 2005-3711
Titre abrégé: J Korean Neurosurg Soc
Pays: Korea (South)
ID NLM: 101467054
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
21
04
2020
accepted:
29
07
2020
entrez:
15
3
2021
pubmed:
16
3
2021
medline:
16
3
2021
Statut:
ppublish
Résumé
Spinal dysraphic lesions due to focal nondisjunction in primary neurulation are commonly encountered in paediatric neurosurgery, but the "fog-of-war" on these conditions was only gradually dispersed in the past 10 years by the works of the groups led by the senior author and Prof. Kyu-Chang Wang. It is now clear that limited dorsal myeloschisis and congenital spinal dermal sinus tract are conditions at the two ends of a spectrum; and mixed lesions of them with various configurations exist. This review article summarizes the current understanding of these conditions' embryogenetic mechanisms, pathological anatomy and clinical manifestations, and their management strategy and surgical techniques.
Identifiants
pubmed: 33715322
pii: jkns.2020.0117
doi: 10.3340/jkns.2020.0117
pmc: PMC7969048
doi:
Types de publication
Journal Article
Langues
eng
Pagination
151-188Références
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