Short durations of corticosteroids for hospitalised COVID-19 patients are associated with a high readmission rate.
COVID-19
Corticosteroids
Dexamethasone
Hospital
Readmissions
Journal
The Journal of infection
ISSN: 1532-2742
Titre abrégé: J Infect
Pays: England
ID NLM: 7908424
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
06
03
2021
accepted:
08
03
2021
pubmed:
16
3
2021
medline:
20
5
2021
entrez:
15
3
2021
Statut:
ppublish
Résumé
Our objective was to describe the characteristics of patients admitted, discharged and readmitted, due to COVID-19, to a central London acute-care hospital during the second peak, in particular in relation to corticosteroids use. We reviewed patients admitted from the community to University College Hospital (UCH) with COVID-19 as their primary diagnosis between 1st-31st December 2020. Re-attendance and readmission data were collected for patients who re-presented within 10 days following discharge. Data were retrospectively collected. 196 patients were admitted from the community with a diagnosis of COVID-19 and discharged alive in December 2020. Corticosteroids were prescribed in hospital for a median of 5 days (IQR 3-8). 20 patients (10.2%) were readmitted within 10 days. 11/20 received corticosteroids in the first admission of which 10 had received 1-3 days of corticosteroids. Readmission rate in those receiving 1-3 days of corticosteroids was 25%. Most international guidelines have recommended providing up to 10 days of corticosteroids for severe COVID-19 but stopping on discharge. Our findings show shorter courses of corticosteroids during admission are associated with an increased risk of being readmitted and support continuing the course of corticosteroids after hospital discharge monitored in the virtual ward setting.
Identifiants
pubmed: 33716109
pii: S0163-4453(21)00115-8
doi: 10.1016/j.jinf.2021.03.002
pmc: PMC7948670
pii:
doi:
Substances chimiques
Adrenal Cortex Hormones
0
Types de publication
Letter
Comment
Langues
eng
Sous-ensembles de citation
IM
Pagination
276-316Subventions
Organisme : Medical Research Council
ID : MC_UU_00004/04
Pays : United Kingdom
Commentaires et corrections
Type : CommentOn
Informations de copyright
Copyright © 2021. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of Competing Interest No conflicts of interests declared by an author.
Références
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