Chemotranscriptomic Profiling Defines Drug-Specific Signatures of the Glycopeptide Antibiotics Dalbavancin, Vancomycin and Chlorobiphenyl-Vancomycin in a VanB-Type-Resistant Streptomycete.
Streptomyces
antibiotic
chemotranscriptomics
dalbavancin
glycopeptide
resistance
vancomycin
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2021
2021
Historique:
received:
14
12
2020
accepted:
05
02
2021
entrez:
15
3
2021
pubmed:
16
3
2021
medline:
16
3
2021
Statut:
epublish
Résumé
Dalbavancin, vancomycin and chlorobiphenyl-vancomycin share a high degree of structural similarity and the same primary mode of drug action. All inhibit bacterial cell wall biosynthesis through complexation with intermediates in peptidoglycan biosynthesis mediated via interaction with peptidyl-d-alanyl-d-alanine (d-Ala-d-Ala) residues present at the termini of the intermediates. VanB-type glycopeptide resistance in bacteria encodes an inducible reprogramming of bacterial cell wall biosynthesis that generates precursors terminating with d-alanyl-d-lactate (d-Ala-d-Lac). This system in
Identifiants
pubmed: 33717038
doi: 10.3389/fmicb.2021.641756
pmc: PMC7947799
doi:
Types de publication
Journal Article
Langues
eng
Pagination
641756Informations de copyright
Copyright © 2021 Hesketh, Bucca, Smith and Hong.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Am Chem Soc. 2014 Oct 1;136(39):13522-5
pubmed: 25211770
Mol Microbiol. 2006 Feb;59(3):923-35
pubmed: 16420361
J Am Chem Soc. 2012 Mar 14;134(10):4637-45
pubmed: 22352468
Nucleic Acids Res. 2015 Apr 20;43(7):e47
pubmed: 25605792
Sci Rep. 2016 Jan 22;6:19602
pubmed: 26797186
Science. 2014 Apr 11;344(6180):208-11
pubmed: 24723613
BMC Genomics. 2018 Jun 14;19(1):457
pubmed: 29898657
Antimicrob Agents Chemother. 2020 Feb 21;64(3):
pubmed: 31907190
Front Microbiol. 2018 Jun 07;9:1175
pubmed: 29930540
Bioinformatics. 2009 Mar 15;25(6):765-71
pubmed: 19176553
J Antimicrob Chemother. 1998 Aug;42(2):199-209
pubmed: 9738837
Annu Rev Pharmacol Toxicol. 2002;42:381-408
pubmed: 11807177
J Bacteriol. 2020 Apr 9;202(9):
pubmed: 32094162
Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):793-8
pubmed: 14718668
Clin Infect Dis. 2012 Apr;54 Suppl 3:S214-9
pubmed: 22431851
Annu Rev Microbiol. 1984;38:339-57
pubmed: 6388496
Nucleic Acids Res. 2019 Jan 25;47(2):621-633
pubmed: 30371884
Biochemistry. 1991 Oct 29;30(43):10408-15
pubmed: 1931965
Clin Microbiol Rev. 2010 Jan;23(1):99-139
pubmed: 20065327
J Biol Chem. 2004 Sep 17;279(38):40174-84
pubmed: 15247240
Mol Microbiol. 2019 Aug;112(2):461-481
pubmed: 30907454
Angew Chem Int Ed Engl. 2020 Jun 26;59(27):10899-10903
pubmed: 32297389
Nucleic Acids Res. 2016 Jan 4;44(D1):D1214-9
pubmed: 26467479
Sci Rep. 2017 Jul 7;7(1):4893
pubmed: 28687742
Antimicrob Agents Chemother. 2004 Aug;48(8):2838-44
pubmed: 15273089
Nucleic Acids Res. 2018 Jun 20;46(11):5692-5703
pubmed: 29746664
OMICS. 2012 May;16(5):284-7
pubmed: 22455463
Nat Biotechnol. 2016 May;34(5):525-7
pubmed: 27043002
J Antimicrob Chemother. 1998 Sep;42(3):315-20
pubmed: 9786471
Microb Ecol. 2017 Apr;73(3):658-667
pubmed: 27896376
Mol Microbiol. 2004 May;52(4):1107-21
pubmed: 15130128
Bioorg Med Chem Lett. 2015 Dec 1;25(23):5477-80
pubmed: 26525861
J Antibiot (Tokyo). 2014 Sep;67(9):631-44
pubmed: 25118105
Nat Commun. 2020 Oct 16;11(1):5232
pubmed: 33067466
Biochemistry. 1991 Feb 26;30(8):2017-21
pubmed: 1998664
Bioinformatics. 2016 Oct 1;32(19):3047-8
pubmed: 27312411
Biotechnol Adv. 2018 Mar - Apr;36(2):534-554
pubmed: 29454983
Antibiotics (Basel). 2020 Feb 13;9(2):
pubmed: 32069930
Chem Rev. 2017 Sep 27;117(18):11952-11993
pubmed: 28437097
Chem Biol. 2002 Nov;9(11):1175-87
pubmed: 12445768
Mol Biol Cell. 2000 Dec;11(12):4241-57
pubmed: 11102521
Mol Microbiol. 2003 Jun;48(5):1289-303
pubmed: 12787356
Chem Biol. 1996 Jan;3(1):21-8
pubmed: 8807824
J Glob Antimicrob Resist. 2013 Jun;1(2):109-113
pubmed: 27873577
Nucleic Acids Res. 2007;35(21):7222-36
pubmed: 17959654
BMC Genomics. 2011 Jul 12;12:361
pubmed: 21749696
Bioorg Med Chem. 2012 Mar 15;20(6):1952-60
pubmed: 22261022
J Biol Chem. 2005 Apr 1;280(13):13055-61
pubmed: 15632111
J Clin Microbiol. 2003 Jan;41(1):5-14
pubmed: 12517819
Antimicrob Agents Chemother. 2014 Oct;58(10):6306-10
pubmed: 25092694
Antibiot Annu. 1955-1956;3:606-11
pubmed: 13355336
ACS Infect Dis. 2018 May 11;4(5):715-735
pubmed: 29363950
Nat Commun. 2016 Jun 02;7:11605
pubmed: 27251447
J Am Chem Soc. 2002 Aug 7;124(31):9064-5
pubmed: 12149006