Pill to Pain: First Case of Topiramate-Induced Chronic Spontaneous Coronary Artery Dissection (SCAD).
chronic migraine
chronic scad
coronary artery angiography
scad management
scad types
topiramate
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
10 Feb 2021
10 Feb 2021
Historique:
entrez:
15
3
2021
pubmed:
16
3
2021
medline:
16
3
2021
Statut:
epublish
Résumé
Spontaneous coronary artery dissection (SCAD) is a non-traumatic, non-iatrogenic, and non-atherosclerotic coronary artery disorder that manifests clinically as acute coronary syndrome (ACS), arrhythmia, or sudden cardiac death (SCD). It is a rare cause of ACS (1.7%-4%) and SCD (0.5%), more common in women than men. It was first reported in 1931 in a 42-year-old female at autopsy, who had SCAD after violent retching and vomiting. We report a case of a 51-year-old female who developed sudden-onset chest pain after taking topiramate (TPM). Her chest pain persisted for 1.5 months prior to her outpatient evaluation, which led to further cardiac workup. An urgent left heart catheterization (LHC) revealed a SCAD. Her symptoms improved with percutaneous coronary intervention (PCI), and she was discharged home on aspirin, statins, and beta-blockers.
Identifiants
pubmed: 33717765
doi: 10.7759/cureus.13263
pmc: PMC7954197
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e13263Informations de copyright
Copyright © 2021, Rahman et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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