Machine Learning Based on Multi-Parametric MRI to Predict Risk of Breast Cancer.

breast cancer machine learning multi-parametric MRI nomogram risk prediction

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2021
Historique:
received: 08 06 2020
accepted: 18 01 2021
entrez: 15 3 2021
pubmed: 16 3 2021
medline: 16 3 2021
Statut: epublish

Résumé

Machine learning (ML) can extract high-throughput features of images to predict disease. This study aimed to develop nomogram of multi-parametric MRI (mpMRI) ML model to predict the risk of breast cancer. The mpMRI included non-enhanced and enhanced T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), apparent diffusion coefficient (ADC), This study involved 144 malignant lesions and 66 benign lesions. The average age of patients with benign and malignant lesions was 42.5 years old and 50.8 years old, respectively, which were statistically different. The sixth and fourth principal components of Nomogram could improve the ability of breast cancer prediction preoperatively.

Identifiants

pubmed: 33718131
doi: 10.3389/fonc.2021.570747
pmc: PMC7952867
doi:

Types de publication

Journal Article

Langues

eng

Pagination

570747

Informations de copyright

Copyright © 2021 Tao, Lu, Zhou, Montemezzi, Bai, Yue, Li, Zhao, Zhou and Lu.

Déclaration de conflit d'intérêts

YY, XL, and LZ were employed by the company of Deepwise. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Weijing Tao (W)

Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Department of Nuclear Medicine, The Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University, Huai'an, China.

Mengjie Lu (M)

Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.

Xiaoyu Zhou (X)

Faculty of Mechanical Electronic and Information Engineering, Jiangsu Vocational College of Finance and Economics, Huai'an, China.

Stefania Montemezzi (S)

Radiology Unit, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata-Verona, Verona, Italy.

Genji Bai (G)

Department of Radiology, The Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University, Huai'an, China.

Yangming Yue (Y)

Deepwise AI Laboratory, Deepwise Inc., Beijing, China.

Xiuli Li (X)

Deepwise AI Laboratory, Deepwise Inc., Beijing, China.

Lun Zhao (L)

Deepwise AI Laboratory, Deepwise Inc., Beijing, China.

Changsheng Zhou (C)

Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.

Guangming Lu (G)

Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.

Classifications MeSH