SARS-CoV-2-Specific Memory T Lymphocytes From COVID-19 Convalescent Donors: Identification, Biobanking, and Large-Scale Production for Adoptive Cell Therapy.
COVID-19
adoptive cell therapy (ACT)
biobank
lymphopenia
memory T cells (Tmem)
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2021
2021
Historique:
received:
23
10
2020
accepted:
01
02
2021
entrez:
15
3
2021
pubmed:
16
3
2021
medline:
16
3
2021
Statut:
epublish
Résumé
Syndrome coronavirus 2 (SARS-CoV-2) pandemic is causing a second outbreak significantly delaying the hope for the virus' complete eradication. In the absence of effective vaccines, we need effective treatments with low adverse effects that can treat hospitalized patients with COVID-19 disease. In this study, we determined the existence of SARS-CoV-2-specific T cells within CD45RA
Identifiants
pubmed: 33718360
doi: 10.3389/fcell.2021.620730
pmc: PMC7947351
doi:
Types de publication
Journal Article
Langues
eng
Pagination
620730Informations de copyright
Copyright © 2021 Ferreras, Pascual-Miguel, Mestre-Durán, Navarro-Zapata, Clares-Villa, Martín-Cortázar, De Paz, Marcos, Vicario, Balas, García-Sánchez, Eguizabal, Solano, Mora-Rillo, Soria and Pérez-Martínez.
Déclaration de conflit d'intérêts
CF, BS, and AP-M filed a patent on this topic. BS received fees from Celgene, Gilead, Sanofi and Novo-Nordisk unrelated to this work. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Vaccine. 2016 Apr 12;34(17):2008-14
pubmed: 26954467
Cell. 2020 Oct 1;183(1):158-168.e14
pubmed: 32979941
Clin Cancer Res. 2017 Oct 1;23(19):5824-5835
pubmed: 28659311
Bone Marrow Transplant. 2015 Jul;50(7):968-77
pubmed: 25665048
Clin Infect Dis. 2020 Jul 28;71(15):762-768
pubmed: 32161940
Front Immunol. 2017 Jan 23;8:19
pubmed: 28167943
JAMA. 2020 May 26;323(20):2085-2086
pubmed: 32293646
J Infect Public Health. 2020 Sep;13(9):1187-1195
pubmed: 32773212
Annu Rev Immunol. 2013;31:137-61
pubmed: 23215646
Adv Cell Gene Ther. 2020 Jul 31;:e101
pubmed: 32838213
Blood. 2013 Jun 27;121(26):5113-23
pubmed: 23610374
Immunol Res. 2014 Aug;59(1-3):118-28
pubmed: 24845462
N Engl J Med. 2021 Feb 25;384(8):693-704
pubmed: 32678530
Immunology. 2002 Jun;106(2):127-38
pubmed: 12047742
Nat Med. 2020 Aug;26(8):1200-1204
pubmed: 32555424
Cell. 2020 Jun 25;181(7):1489-1501.e15
pubmed: 32473127
F1000 Biol Rep. 2010 Sep 08;2:67
pubmed: 21173876
Nat Rev Immunol. 2014 Jan;14(1):24-35
pubmed: 24336101
Lancet. 2020 May 16;395(10236):1569-1578
pubmed: 32423584
J Immunol. 2001 Jan 15;166(2):877-84
pubmed: 11145663
Cell. 2021 Jan 7;184(1):169-183.e17
pubmed: 33296701
Bone Marrow Transplant. 2014 Jan;49(1):138-44
pubmed: 23933765
Int J Infect Dis. 2020 Jul;96:131-135
pubmed: 32376308
J Clin Invest. 2015 Jul 1;125(7):2677-89
pubmed: 26053664
Biol Blood Marrow Transplant. 2014 May;20(5):705-16
pubmed: 24525279
Nat Rev Drug Discov. 2020 May;19(5):305-306
pubmed: 32273591
Adv Physiol Educ. 2013 Dec;37(4):273-83
pubmed: 24292902
Transpl Infect Dis. 2018 Feb;20(1):
pubmed: 29178554
J Immunol. 2008 Oct 15;181(8):5490-500
pubmed: 18832706
J Immunol. 2006 Sep 1;177(5):2775-83
pubmed: 16920912
Lancet. 2020 Oct 5;:
pubmed: 33031761
Nat Immunol. 2020 Nov;21(11):1336-1345
pubmed: 32887977
Nat Commun. 2020 Sep 17;11(1):4704
pubmed: 32943637
Virus Res. 2020 Aug;285:198005
pubmed: 32408156
N Engl J Med. 2020 Sep 10;383(11):1085-1087
pubmed: 32706954
Front Immunol. 2019 Oct 10;10:2361
pubmed: 31649672
Cell Mol Immunol. 2014 Jul;11(4):387-97
pubmed: 24658435
EClinicalMedicine. 2020 Aug;25:100454
pubmed: 32838232