Multicellular Systems to Translate Somatic Cell Genome Editors to Humans.
Adaptive immunity
CRISPR-Cas
Off-target effects
Organ-on-chips
Organoids
Journal
Current opinion in biomedical engineering
ISSN: 2468-4511
Titre abrégé: Curr Opin Biomed Eng
Pays: England
ID NLM: 101704011
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
entrez:
15
3
2021
pubmed:
16
3
2021
medline:
16
3
2021
Statut:
ppublish
Résumé
As genome editors move into clinical trials, there is a need to establish
Identifiants
pubmed: 33718690
doi: 10.1016/j.cobme.2020.100249
pmc: PMC7948211
mid: NIHMS1636993
doi:
Types de publication
Journal Article
Langues
eng
Pagination
72-81Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL141805
Pays : United States
Organisme : NIBIB NIH HHS
ID : U01 EB029372
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK127713
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB024562
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL145794
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB028532
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK120531
Pays : United States
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Références
Nat Rev Mater. 2019 Jun;4(6):355-378
pubmed: 31903226
Science. 2019 Jun 07;364(6444):960-965
pubmed: 31171693
Trends Biotechnol. 2015 Feb;33(2):132-40
pubmed: 25595557
Nat Biotechnol. 2018 Sep;36(8):765-771
pubmed: 30010673
Science. 2017 Nov 24;358(6366):1019-1027
pubmed: 29070703
Nat Biomed Eng. 2019 Oct;3(10):806-816
pubmed: 31332341
Nat Rev Drug Discov. 2017 Jun;16(6):387-399
pubmed: 28337020
Nat Med. 2019 Feb;25(2):249-254
pubmed: 30692695
Nat Commun. 2019 Apr 23;10(1):1842
pubmed: 31015529
Nat Biomed Eng. 2020 Apr;4(4):407-420
pubmed: 31988458
Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10539-E10547
pubmed: 30348765
Biomed J. 2014 Sep-Oct;37(5):246-58
pubmed: 25163502
Science. 2019 Apr 19;364(6437):286-289
pubmed: 31000663
Cell Stem Cell. 2020 Mar 5;26(3):309-329
pubmed: 32142662
Trends Biotechnol. 2017 Feb;35(2):172-183
pubmed: 27592803
Nature. 2016 Jan 28;529(7587):490-5
pubmed: 26735016
Nat Biotechnol. 2019 Mar;37(3):276-282
pubmed: 30742127
Nature. 2015 Apr 9;520(7546):186-91
pubmed: 25830891
Genome Biol. 2019 Jan 17;20(1):14
pubmed: 30654827
Cell Syst. 2020 Mar 25;10(3):223-239.e9
pubmed: 32191873
Nature. 2020 Feb;578(7794):229-236
pubmed: 32051598
Emerg Top Life Sci. 2019 May 31;3(3):327-334
pubmed: 33523136
Cell Stem Cell. 2015 May 7;16(5):556-65
pubmed: 25891906
Science. 2018 Jan 12;359(6372):
pubmed: 29326244
Drug Discov Today. 2019 Feb;24(2):517-525
pubmed: 30312743
Nat Med. 2017 Sep;23(9):1095-1101
pubmed: 28759051
Nat Biomed Eng. 2020 Apr;4(4):421-436
pubmed: 31988459
Elife. 2020 Jan 14;9:
pubmed: 31933478
Nat Mater. 2019 Apr;18(4):397-405
pubmed: 30778227
Gastroenterology. 2019 Feb;156(3):562-576
pubmed: 30476497
Trends Biotechnol. 2018 Feb;36(2):173-185
pubmed: 29305085
Nat Rev Genet. 2016 May;17(5):300-12
pubmed: 27087594
Annu Rev Biophys. 2017 May 22;46:505-529
pubmed: 28375731
Mol Ther. 2016 Mar;24(3):475-87
pubmed: 26750397
Mol Ther Methods Clin Dev. 2018 Jun 15;10:105-112
pubmed: 30073181
Nat Methods. 2016 Oct;13(10):868-74
pubmed: 27595405
Sci Rep. 2018 Mar 14;8(1):4530
pubmed: 29540740
Arch Toxicol. 2019 Feb;93(2):401-416
pubmed: 30552464
Am J Transplant. 2016 Feb;16(2):389-97
pubmed: 26588186
Science. 2019 Jun 07;364(6444):956-959
pubmed: 31171692
Cell Stem Cell. 2017 Sep 7;21(3):297-300
pubmed: 28886364
Development. 2017 Mar 15;144(6):958-962
pubmed: 28292841
Nat Methods. 2017 Jun;14(6):607-614
pubmed: 28459458
Front Immunol. 2019 Nov 19;10:2694
pubmed: 31803196
Nature. 2019 Dec;576(7785):149-157
pubmed: 31634902
Cell Stem Cell. 2018 Mar 1;22(3):310-324
pubmed: 29499151
Nature. 2018 Apr;556(7700):239-243
pubmed: 29618819
Cell. 2019 Jun 27;178(1):122-134.e12
pubmed: 31230714
Exp Cell Res. 2018 Feb 1;363(1):15-25
pubmed: 29291400
Science. 2014 Jul 18;345(6194):1247125
pubmed: 25035496
Dev Cell. 2016 Sep 26;38(6):590-600
pubmed: 27676432
Nat Rev Drug Discov. 2018 Oct;17(10):689-690
pubmed: 29930285
Sci Transl Med. 2019 Nov 6;11(517):
pubmed: 31694927
Cell. 2018 Jan 11;172(1-2):373-386.e10
pubmed: 29224780
Drug Metab Dispos. 2015 Jul;43(7):1091-9
pubmed: 25926431
Nat Methods. 2019 Mar;16(3):255-262
pubmed: 30742039
Cell Stem Cell. 2020 Feb 6;26(2):161-171.e4
pubmed: 31839569
J Pharm Sci. 2020 Jan;109(1):62-67
pubmed: 31589876
Hum Gene Ther. 2015 Jul;26(7):432-42
pubmed: 26086867
Front Bioeng Biotechnol. 2019 Mar 19;7:39
pubmed: 30941347
J Am Chem Soc. 2018 May 30;140(21):6596-6603
pubmed: 29668265
Cell Stem Cell. 2020 Apr 2;26(4):503-510.e7
pubmed: 32084388
Science. 2012 Aug 17;337(6096):816-21
pubmed: 22745249
Nat Commun. 2016 Jan 06;7:10243
pubmed: 26732624
Genome Res. 2018 Feb 22;:
pubmed: 29472270
Cell Stem Cell. 2013 Dec 5;13(6):653-8
pubmed: 24315439
Sci Rep. 2018 Jan 17;8(1):888
pubmed: 29343825
Cell. 2020 Apr 2;181(1):136-150
pubmed: 32243786
Cell Stem Cell. 2019 Jun 6;24(6):841-842
pubmed: 31173713
Cell. 2017 Jan 12;168(1-2):20-36
pubmed: 27866654