Ingesting Yogurt Containing
HOMA-IR
Lactobacillus plantarum
abdominal fat area
chronic inflammation
fasting plasma glucose
high-sensitivity C-reactive protein
insulin resistance
interleukin-6
yogurt
Journal
Current developments in nutrition
ISSN: 2475-2991
Titre abrégé: Curr Dev Nutr
Pays: United States
ID NLM: 101717957
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
31
12
2020
revised:
20
01
2021
accepted:
26
01
2021
entrez:
15
3
2021
pubmed:
16
3
2021
medline:
16
3
2021
Statut:
epublish
Résumé
Chronic inflammation and insulin resistance are factors that are related to obesity. We have suggested that the administration of heat-treated The aim of this study was to investigate whether ingesting OLL2712 cells can reduce body fat accumulation and improve metabolic risk factors, in overweight, healthy adults. This study was a randomized, double-blind, placebo-controlled, parallel-group trial conducted at a single center in Japan. The study participants included 100 overweight (BMI range, ≥25 to <30 kg/m The 12-wk change of abdominal fat area (difference: 8.5 cm The ingestion of heat-treated OLL2712 cells reduces body fat accumulation and the deterioration of glycemic control and chronic inflammation, in overweight, healthy adults. We hypothesize that OLL2712 cells may prevent obesity by regulating chronic inflammation. This trial was registered at the University Hospital Medical Information Network Clinical Trials Registry as UMIN000027709.
Sections du résumé
BACKGROUND
BACKGROUND
Chronic inflammation and insulin resistance are factors that are related to obesity. We have suggested that the administration of heat-treated
OBJECTIVE
OBJECTIVE
The aim of this study was to investigate whether ingesting OLL2712 cells can reduce body fat accumulation and improve metabolic risk factors, in overweight, healthy adults.
METHODS
METHODS
This study was a randomized, double-blind, placebo-controlled, parallel-group trial conducted at a single center in Japan. The study participants included 100 overweight (BMI range, ≥25 to <30 kg/m
RESULTS
RESULTS
The 12-wk change of abdominal fat area (difference: 8.5 cm
CONCLUSIONS
CONCLUSIONS
The ingestion of heat-treated OLL2712 cells reduces body fat accumulation and the deterioration of glycemic control and chronic inflammation, in overweight, healthy adults. We hypothesize that OLL2712 cells may prevent obesity by regulating chronic inflammation. This trial was registered at the University Hospital Medical Information Network Clinical Trials Registry as UMIN000027709.
Identifiants
pubmed: 33718754
doi: 10.1093/cdn/nzab006
pii: nzab006
pmc: PMC7937491
doi:
Types de publication
Journal Article
Langues
eng
Pagination
nzab006Informations de copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.
Références
Appl Environ Microbiol. 2017 Mar 17;83(7):
pubmed: 28087537
J Clin Invest. 2007 Jan;117(1):175-84
pubmed: 17200717
J Hepatol. 2008 Apr;48(4):628-37
pubmed: 18267346
J Clin Invest. 2003 Dec;112(12):1821-30
pubmed: 14679177
Med Sci Sports Exerc. 1988 Oct;20(5):489-91
pubmed: 3193865
Am J Clin Nutr. 2016 Apr;103(4):1111-24
pubmed: 26912494
Biosci Microbiota Food Health. 2020;39(2):39-44
pubmed: 32328399
Diabetes. 2009 Nov;58(11):2525-35
pubmed: 19690064
Nat Med. 2009 Aug;15(8):921-9
pubmed: 19633657
Diabetes. 2009 Nov;58(11):2574-82
pubmed: 19690061
Ann Intern Med. 2010 Jun 1;152(11):726-32
pubmed: 20335313
J Nutr. 2017 Jul;147(7):1468S-1475S
pubmed: 28615382
Arch Intern Med. 2007 Jan 8;167(1):31-9
pubmed: 17210875
Front Microbiol. 2017 Sep 22;8:1765
pubmed: 29018410
Gastroenterology. 2017 May;152(7):1671-1678
pubmed: 28192102
J Nutr. 2017 Jul;147(7):1462S-1467S
pubmed: 28615381
J Nutr Sci Vitaminol (Tokyo). 2013;59(2):144-7
pubmed: 23727645
Diabetes Care. 2006 Jun;29(6):1337-44
pubmed: 16732018
Hypertens Res. 2013 May;36(5):398-402
pubmed: 23235713
Nat Med. 2019 Jul;25(7):1096-1103
pubmed: 31263284
J Intern Med. 2017 Apr;281(4):319-336
pubmed: 27991713
Nutrients. 2020 Jan 31;12(2):
pubmed: 32023901
Eur J Nutr. 2019 Feb;58(1):27-43
pubmed: 30043184
Eur J Nutr. 2017 Jun;56(4):1375-1392
pubmed: 27807623
Radiology. 1999 Apr;211(1):283-6
pubmed: 10189485
J Physiol Anthropol. 2012 May 04;31:10
pubmed: 22738323
Annu Rev Immunol. 2011;29:415-45
pubmed: 21219177
PLoS One. 2017 Mar 1;12(3):e0173004
pubmed: 28249045
Front Microbiol. 2020 Feb 21;11:219
pubmed: 32153527
Front Microbiol. 2019 May 24;10:1046
pubmed: 31191465
Int J Obes. 1983;7(5):437-45
pubmed: 6642855
Int Immunol. 2018 Jun 26;30(7):319-331
pubmed: 29767727
Adv Nutr. 2017 Jan 17;8(1):146S-154S
pubmed: 28096138
Int J Epidemiol. 2017 Apr 1;46(2):746-755
pubmed: 28025257
J Atheroscler Thromb. 2010 Jun 30;17(6):638-43
pubmed: 20215703
Hypertens Res. 2010 Jun;33(6):568-72
pubmed: 20300109
Br J Nutr. 2015 Oct 14;114(7):999-1012
pubmed: 26228057
Adv Nutr. 2018 May 1;10(suppl_2):S239-S250
pubmed: 31089732
Nat Rev Mol Cell Biol. 2008 May;9(5):367-77
pubmed: 18401346
Gut. 2019 Aug;68(8):1516-1526
pubmed: 31076401
Nutrition. 2019 Feb;58:175-180
pubmed: 30502681
Diabetes Res Clin Pract. 2017 Jun;128:40-50
pubmed: 28437734
Cell Metab. 2016 Aug 9;24(2):295-310
pubmed: 27508875
Am J Clin Nutr. 2000 Mar;71(3):674-81
pubmed: 10702159
Microb Pathog. 2012 Aug;53(2):100-8
pubmed: 22634320
Int J Obes Relat Metab Disord. 1994 Apr;18(4):219-34
pubmed: 8044196
J Sports Med Phys Fitness. 1993 Jun;33(2):172-7
pubmed: 8412053
Biosci Microbiota Food Health. 2016;35(4):163-171
pubmed: 27867803
Am J Clin Nutr. 2004 May;79(5):907S-912S
pubmed: 15113738
Nutr Metab Cardiovasc Dis. 2014 Oct;24(10):1105-11
pubmed: 24954422
Eur J Clin Nutr. 2010 Jun;64(6):636-43
pubmed: 20216555
BMC Med. 2014 Nov 25;12:215
pubmed: 25420418
Gastroenterology. 2007 May;132(6):2169-80
pubmed: 17498510
Nutrients. 2017 Dec 01;9(12):
pubmed: 29194424
J Dairy Sci. 2016 Feb;99(2):933-946
pubmed: 26686731
Am J Clin Nutr. 2004 Apr;79(4):544-51
pubmed: 15051595
Diabetologia. 1985 Jul;28(7):412-9
pubmed: 3899825
Am J Clin Nutr. 2019 Jun 1;109(6):1611-1619
pubmed: 31136662
Eur J Nutr. 2018 Jun;57(4):1591-1603
pubmed: 28577150