A Safe Way to Administer Drugs Through a Nutrition Tube-The Simple Suspension Method.
Clogging
Deglutition
Deglutition disorders
Tablets
Tube feeding
Warm water
Journal
Dysphagia
ISSN: 1432-0460
Titre abrégé: Dysphagia
Pays: United States
ID NLM: 8610856
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
22
07
2020
accepted:
24
02
2021
pubmed:
16
3
2021
medline:
31
3
2022
entrez:
15
3
2021
Statut:
ppublish
Résumé
The simple suspension method (SSM), developed by Kurata in 1997, is a way to suspend tablets and capsules in warm water for decay and suspension prior to their administration. This method is safe and has various advantages such as the avoidance of tube clogging and the loss of the drug. This study aimed to investigate whether a higher percentage of commonly used drugs could pass through nutrition tubes effectively using SSM, relative to that using the conventional crushing method. A tablet or capsule was inserted into a 20 mL syringe with warm water (at 55 °C). After 10 min, it was shaken in the syringe. The suspension liquid was injected into tubes of the following sizes: 8 Fr, 10 Fr, 12 Fr, 14 Fr, 16 Fr, and 18 Fr. A total of 3686 tablets and 432 capsules that are frequently used in Japan were tested. Using SSM, 3377 (91.6%) tablets and 359 (83.1%) capsules disintegrated within 10 min and passed through the tube without clogging it in the tube passage test. With the conventional crushing method, 2117 tablets (57.4%) and 272 capsules (63.0%) could be crushed. SSM reduced the risk of tube clogging and drug loss with more drugs than that with the conventional crushing method. The number of drugs indicated for administration by SSM is greater than that indicated by the conventional crushing method. Further studies are needed to consider its utility compared to conventional methods for dysphagia patients in clinical settings.
Identifiants
pubmed: 33719015
doi: 10.1007/s00455-021-10280-w
pii: 10.1007/s00455-021-10280-w
pmc: PMC8948140
doi:
Substances chimiques
Suspensions
0
Tablets
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
318-322Informations de copyright
© 2021. The Author(s).
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