Update on molecular biomarkers for diagnosis and prediction of prognosis and treatment responses in gastric cancer.
Journal
Histology and histopathology
ISSN: 1699-5848
Titre abrégé: Histol Histopathol
Pays: Spain
ID NLM: 8609357
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
pubmed:
16
3
2021
medline:
9
3
2022
entrez:
15
3
2021
Statut:
ppublish
Résumé
Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide, and its high mortality rate is a serious problem in many regions. To improve prognosis, it is necessary to identify novel biomarkers for the early detection of GC, along with its prognosis, risk of metastatic recurrence, and predicted response to chemotherapy, and to develop individualized treatment strategies. Advances in microarray and sequencing techniques have led to the elucidation of cancer-related gene mutations and aberrant expression levels, which have deepened our knowledge of GC. Further searches for sensitive biomarkers are needed to improve the management of patients with GC. In this review article, we update the current knowledge of GC biomarkers, examine recently published literature, and introduce some representative molecules.
Identifiants
pubmed: 33719028
pii: HH-18-326
doi: 10.14670/HH-18-326
doi:
Substances chimiques
Biomarkers, Tumor
0
MicroRNAs
0
RNA, Long Noncoding
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
817-832Références
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