Graphene Oxide and Stabilized Ortho-Silicic Acid as Modifiers of Amnion and Burn Affected Skin: A Comparative Study.
L-ascorbic acid
graphene oxide
sodium ascorbate
stabilized ortho-silicic acid
Journal
Nanotechnology, science and applications
ISSN: 1177-8903
Titre abrégé: Nanotechnol Sci Appl
Pays: New Zealand
ID NLM: 101524435
Informations de publication
Date de publication:
2021
2021
Historique:
received:
03
12
2020
accepted:
03
02
2021
entrez:
17
3
2021
pubmed:
18
3
2021
medline:
18
3
2021
Statut:
epublish
Résumé
Oxidative tissue damage caused by reactive oxygen species results in a significant decrease in the total antioxidant capacity of the biological system. The aim of this interdisciplinary study was to answer the question of whether active antioxidants modify, at a molecular and supramolecular level, the tissue of pathological amnion and the necrotic eschar degraded in thermal burn. A Nicolet 6700 Fourier-transform spectrophotometer with OMNIC software and the EasiDiff diffusion accessory were used in the FTIR spectroscopic analysis. A NICOLET MAGNA-IR 860 spectrometer with FT-Raman accessory was used to record the Raman spectra of the samples. The samples were exposed to bacteria capable of causing nosocomial infections, ie Gram-positive The infrared spectroscopy analysis proved that after modification of the amniotic samples in graphene oxide and ortho-silicic acid, the amide II band is split into two components. Incubation of samples in modifier solutions: graphene oxide, sodium ascorbate and L-ascorbic acid results in shifts and changes of intensity within the broadly understood lipid band 1743-1745-1747 cm This thermogravimetric study found the highest stability of the analysed tissues (hypotrophic amnion and burnt epidermis) after modification with graphene oxide and sodium ascorbate.
Identifiants
pubmed: 33727805
doi: 10.2147/NSA.S294412
pii: 294412
pmc: PMC7955732
doi:
Types de publication
Journal Article
Langues
eng
Pagination
49-67Informations de copyright
© 2021 Pielesz et al.
Déclaration de conflit d'intérêts
Dr Henk-Maarten Laane is an employee of ReXil Agro BV and reports a patent on the stabilisation of silicic acid. The authors report no other potential conflicts of interest for this work.
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