Contralateral neck failure in oral tongue cancer: Outcomes from two centers using predefined treatment criteria.
contralateral lymph node metastasis
head and neck cancer
oral tongue squamous cell carcinoma
radiation therapy
surgery
Journal
Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
revised:
14
12
2020
received:
22
08
2020
accepted:
26
02
2021
pubmed:
18
3
2021
medline:
2
7
2021
entrez:
17
3
2021
Statut:
ppublish
Résumé
The objective was to determine the incidence of, and factors associated with contralateral neck failure (CNF) in oral tongue squamous cell carcinoma (OTSCC). Consecutive patients with OTSCC between 2007 and 2016 were included. The predefined policy of the contralateral neck included neck dissection (ND) where the primary tumor extended/crossed midline or the contralateral neck was involved; and elective nodal irradiation (ENI) where the primary tumor was ≤1 cm from midline/2 cm from tip. This study included 258 patients. ND was ipsilateral 169 (66%) and bilateral 33 (13%). Fifty-five patients (21%) received ENI to the undissected contralateral neck. CNF occurred in 19 patients (7%) and was similar by treatment received. Utilizing this approach, we observed higher rates of CNF with increasing N classification, perineural invasion, extracapsular extension, and depth of invasion ≥6 mm. Using our institutional policy of treatment to the contralateral neck, a low rate of CNF (≤10%) was observed.
Sections du résumé
BACKGROUND
The objective was to determine the incidence of, and factors associated with contralateral neck failure (CNF) in oral tongue squamous cell carcinoma (OTSCC).
METHODS
Consecutive patients with OTSCC between 2007 and 2016 were included. The predefined policy of the contralateral neck included neck dissection (ND) where the primary tumor extended/crossed midline or the contralateral neck was involved; and elective nodal irradiation (ENI) where the primary tumor was ≤1 cm from midline/2 cm from tip.
RESULTS
This study included 258 patients. ND was ipsilateral 169 (66%) and bilateral 33 (13%). Fifty-five patients (21%) received ENI to the undissected contralateral neck. CNF occurred in 19 patients (7%) and was similar by treatment received. Utilizing this approach, we observed higher rates of CNF with increasing N classification, perineural invasion, extracapsular extension, and depth of invasion ≥6 mm.
CONCLUSIONS
Using our institutional policy of treatment to the contralateral neck, a low rate of CNF (≤10%) was observed.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2024-2031Informations de copyright
© 2021 Wiley Periodicals LLC.
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