Inhibition of platelet-derived growth factor receptor synergistically increases the pharmacological effect of tamoxifen in estrogen receptor α positive breast cancer.
cell cycle arrest
estrogen receptor-α+ breast cance
platelet-derived growth factor receptor α
platelet-derived growth factor receptor β
platelet-derived growth factor-BB
Journal
Oncology letters
ISSN: 1792-1074
Titre abrégé: Oncol Lett
Pays: Greece
ID NLM: 101531236
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
24
07
2020
accepted:
01
02
2021
entrez:
18
3
2021
pubmed:
19
3
2021
medline:
19
3
2021
Statut:
ppublish
Résumé
The platelet-derived growth factor (PDGF) family, a complex and imperative group of proangiogenic factors, acts as strong cell growth chemokines and is essential for the progression of malignancy in humans. In the present study, it was observed that aberrant PDGFB expression is associated with survival rates in patients with estrogen receptor-positive (ER
Identifiants
pubmed: 33732370
doi: 10.3892/ol.2021.12555
pii: OL-0-0-12555
pmc: PMC7905523
doi:
Types de publication
Journal Article
Langues
eng
Pagination
294Informations de copyright
Copyright: © Kim et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
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