Nanoparticles exhibiting self-regulating temperature as innovative agents for Magnetic Fluid Hyperthermia.


Journal

Nanotheranostics
ISSN: 2206-7418
Titre abrégé: Nanotheranostics
Pays: Australia
ID NLM: 101698994

Informations de publication

Date de publication:
2021
Historique:
received: 08 01 2021
accepted: 12 02 2021
entrez: 18 3 2021
pubmed: 19 3 2021
medline: 11 5 2021
Statut: epublish

Résumé

During the last few years, for therapeutic purposes in oncology, considerable attention has been focused on a method called magnetic fluid hyperthermia (MFH) based on local heating of tumor cells. In this paper, an innovative, promising nanomaterial, M48 composed of iron oxide-based phases has been tested. M48 shows self-regulating temperature due to the observable second order magnetic phase transition from ferromagnetic to paramagnetic state. A specific hydrophilic coating based on both citrate ions and glucose molecules allows high biocompatibility of the nanomaterial in biological matrices and its use

Identifiants

pubmed: 33732604
doi: 10.7150/ntno.55695
pii: ntnov05p0333
pmc: PMC7961124
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

333-347

Informations de copyright

© The author(s).

Déclaration de conflit d'intérêts

Competing Interests: The authors have declared that no competing interest exists.

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Auteurs

Marco Gerosa (M)

Department of Diagnostics and Public Health, University of Verona, Piazzale L.A. Scuro, 37134 Verona, Italy.

Marco Dal Grande (MD)

Nanomaterials Research Group, Department of Biotechnology, University of Verona and INSTM, RU Verona, Strada Le Grazie 15, I-37134 Verona, Italy.

Alice Busato (A)

Department of Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy.

Federica Vurro (F)

Department of Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.

Barbara Cisterna (B)

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy.

Enrico Forlin (E)

MBN Nanomaterialia S.p.A., Via Giacomo Bortolan, 42, 31050 Carbonera Treviso, Italy.

Filippo Gherlinzoni (F)

Foundation for Nanotheranostics Research in Cancer Therapy, RNC, Treviso, Italy.

Giovanni Morana (G)

Foundation for Nanotheranostics Research in Cancer Therapy, RNC, Treviso, Italy.

Michele Gottardi (M)

Foundation for Nanotheranostics Research in Cancer Therapy, RNC, Treviso, Italy.

Paolo Matteazzi (P)

MBN Nanomaterialia S.p.A., Via Giacomo Bortolan, 42, 31050 Carbonera Treviso, Italy.
Foundation for Nanotheranostics Research in Cancer Therapy, RNC, Treviso, Italy.

Adolfo Speghini (A)

Nanomaterials Research Group, Department of Biotechnology, University of Verona and INSTM, RU Verona, Strada Le Grazie 15, I-37134 Verona, Italy.

Pasquina Marzola (P)

Department of Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.

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Classifications MeSH