Clinical Application of Shear Wave Elastography for Assisting Brain Tumor Resection.
brain tumor
detecting brain tumor residual
elastography
intraoperative ultrasound
shear wave
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2021
2021
Historique:
received:
19
10
2020
accepted:
08
01
2021
entrez:
18
3
2021
pubmed:
19
3
2021
medline:
19
3
2021
Statut:
epublish
Résumé
The clinical outcomes for brain tumor resection have been shown to be significantly improved with increased extent of resection. To achieve this, neurosurgeons employ different intra-operative tools to improve the extent of resection of brain tumors, including ultrasound, CT, and MRI. Young's modulus (YM) of brain tumors have been shown to be different from normal brain but the accuracy of SWE in assisting brain tumor resection has not been reported. To determine the accuracy of SWE in detecting brain tumor residual using post-operative MRI scan as "gold standard". Thirty-four patients (aged 1-62 years, M:F = 15:20) with brain tumors were recruited into the study. The intraoperative SWE scans were performed using Aixplorer The YM of the brain tumors correlated significantly with surgeons' findings ( SWE had a higher sensitivity in detecting residual tumor than the surgeons (94% vs. 36%). However, the surgeons had a higher specificity than SWE (100% vs. 77%). Therefore, using SWE in combination with surgeon's opinion may optimize the detection of residual tumor, and hence improve the extent of brain tumor resection.
Sections du résumé
BACKGROUND
BACKGROUND
The clinical outcomes for brain tumor resection have been shown to be significantly improved with increased extent of resection. To achieve this, neurosurgeons employ different intra-operative tools to improve the extent of resection of brain tumors, including ultrasound, CT, and MRI. Young's modulus (YM) of brain tumors have been shown to be different from normal brain but the accuracy of SWE in assisting brain tumor resection has not been reported.
AIMS
OBJECTIVE
To determine the accuracy of SWE in detecting brain tumor residual using post-operative MRI scan as "gold standard".
METHODS
METHODS
Thirty-four patients (aged 1-62 years, M:F = 15:20) with brain tumors were recruited into the study. The intraoperative SWE scans were performed using Aixplorer
RESULTS
RESULTS
The YM of the brain tumors correlated significantly with surgeons' findings (
CONCLUSIONS
CONCLUSIONS
SWE had a higher sensitivity in detecting residual tumor than the surgeons (94% vs. 36%). However, the surgeons had a higher specificity than SWE (100% vs. 77%). Therefore, using SWE in combination with surgeon's opinion may optimize the detection of residual tumor, and hence improve the extent of brain tumor resection.
Identifiants
pubmed: 33732645
doi: 10.3389/fonc.2021.619286
pmc: PMC7956956
doi:
Types de publication
Journal Article
Langues
eng
Pagination
619286Informations de copyright
Copyright © 2021 Chan, Uff, Chakraborty, Dorward and Bamber.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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