Deactivation of the JNK Pathway by GSTP1 Is Essential to Maintain Sperm Functionality.

GSTP1-JNK heterocomplex ezatiostat mammalian sperm mitochondria sperm functionality

Journal

Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250

Informations de publication

Date de publication:
2021
Historique:
received: 08 11 2020
accepted: 22 01 2021
entrez: 18 3 2021
pubmed: 19 3 2021
medline: 19 3 2021
Statut: epublish

Résumé

Fifty percent of male subfertility diagnosis is idiopathic and is usually associated with genetic abnormalities or protein dysfunction, which are not detectable through the conventional spermiogram. Glutathione

Identifiants

pubmed: 33732696
doi: 10.3389/fcell.2021.627140
pmc: PMC7959831
doi:

Types de publication

Journal Article

Langues

eng

Pagination

627140

Informations de copyright

Copyright © 2021 Llavanera, Mateo-Otero, Delgado-Bermúdez, Recuero, Olives, Barranco and Yeste.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Marc Llavanera (M)

Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain.
Unit of Cell Biology, Department of Biology, Faculty of Sciences, University of Girona, Girona, Spain.

Yentel Mateo-Otero (Y)

Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain.
Unit of Cell Biology, Department of Biology, Faculty of Sciences, University of Girona, Girona, Spain.

Ariadna Delgado-Bermúdez (A)

Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain.
Unit of Cell Biology, Department of Biology, Faculty of Sciences, University of Girona, Girona, Spain.

Sandra Recuero (S)

Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain.
Unit of Cell Biology, Department of Biology, Faculty of Sciences, University of Girona, Girona, Spain.

Samuel Olives (S)

Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain.
Unit of Cell Biology, Department of Biology, Faculty of Sciences, University of Girona, Girona, Spain.

Isabel Barranco (I)

Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain.
Unit of Cell Biology, Department of Biology, Faculty of Sciences, University of Girona, Girona, Spain.

Marc Yeste (M)

Biotechnology of Animal and Human Reproduction (TechnoSperm), Institute of Food and Agricultural Technology, University of Girona, Girona, Spain.
Unit of Cell Biology, Department of Biology, Faculty of Sciences, University of Girona, Girona, Spain.

Classifications MeSH