Population Estimates of GFR and Risk Factors for CKD in Guatemala.
CKD
CKD of unknown etiology
Central America
global health
Journal
Kidney international reports
ISSN: 2468-0249
Titre abrégé: Kidney Int Rep
Pays: United States
ID NLM: 101684752
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
26
11
2020
accepted:
15
12
2020
entrez:
18
3
2021
pubmed:
19
3
2021
medline:
19
3
2021
Statut:
epublish
Résumé
Chronic kidney disease (CKD) is an emerging public health priority in Central America. However, data on the prevalence of CKD in Guatemala, Central America's most populous country, are limited, especially for rural communities. We conducted a population-representative survey of 2 rural agricultural municipalities in Guatemala. We collected anthropometric data, blood pressure, serum and urine creatinine, glycosylated hemoglobin, and urine albumin. Sociodemographic, health, and exposure data were self-reported. We enrolled 807 individuals (63% of all eligible, 35% male, mean age 39.5 years). An estimated 4.0% (95% confidence interval [CI] 2.4-6.6) had CKD, defined as an estimated glomerular filtration rate (eGFR) less than 60 ml/min per 1.73 m In this population-based survey, most observed CKD was associated with diabetes and hypertension. These results emphasize the urgent public health need to address the emerging epidemic of diabetes, hypertension, and CKD in rural Guatemala. In addition, the association between CKD and sugar cane in individuals living in poverty provides some circumstantial evidence for existence of CKD of unknown etiology in the study communities, which requires further investigation.
Identifiants
pubmed: 33732994
doi: 10.1016/j.ekir.2020.12.015
pii: S2468-0249(20)31847-7
pmc: PMC7938058
doi:
Types de publication
Journal Article
Langues
eng
Pagination
796-805Subventions
Organisme : NIDDK NIH HHS
ID : P30 DK092926
Pays : United States
Organisme : FIC NIH HHS
ID : R21 TW010831
Pays : United States
Informations de copyright
© 2020 International Society of Nephrology. Published by Elsevier Inc.
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