Retinal ganglion cell dysfunction in preclinical Alzheimer's disease: an electrophysiologic biomarker signature.
Aged
Alzheimer Disease
/ cerebrospinal fluid
Amyloid beta-Peptides
/ cerebrospinal fluid
Biomarkers
/ cerebrospinal fluid
Electrophysiological Phenomena
Electroretinography
Humans
Middle Aged
Nerve Fibers
/ pathology
Neuropsychological Tests
Peptide Fragments
/ cerebrospinal fluid
Photic Stimulation
Retina
/ diagnostic imaging
Retinal Diseases
/ cerebrospinal fluid
Retinal Ganglion Cells
/ pathology
Tomography, Optical Coherence
Visual Fields
tau Proteins
/ cerebrospinal fluid
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
18 03 2021
18 03 2021
Historique:
received:
05
11
2020
accepted:
20
02
2021
entrez:
19
3
2021
pubmed:
20
3
2021
medline:
13
10
2021
Statut:
epublish
Résumé
The current study evaluated retinal function using electroretinography (ERG) in cognitively healthy (CH) participants with preclinical Alzheimer's disease (AD), as classified by cerebral spinal fluid (CSF) Aβ
Identifiants
pubmed: 33737516
doi: 10.1038/s41598-021-85010-1
pii: 10.1038/s41598-021-85010-1
pmc: PMC7973731
doi:
Substances chimiques
Amyloid beta-Peptides
0
Biomarkers
0
Peptide Fragments
0
amyloid beta-protein (1-42)
0
tau Proteins
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6344Références
Neurology. 2013 Jul 2;81(1):76-83
pubmed: 23709591
J Gen Intern Med. 1991 Mar-Apr;6(2):126-32
pubmed: 2023019
Neurobiol Aging. 1996 May-Jun;17(3):385-95
pubmed: 8725900
Surv Ophthalmol. 2014 Jul-Aug;59(4):414-33
pubmed: 24309127
Arch Neurol. 2009 Mar;66(3):382-9
pubmed: 19273758
Front Psychiatry. 2014 Feb 25;5:22
pubmed: 24616709
J Alzheimers Dis. 2014;40(2):277-83
pubmed: 24413621
Brain Res Bull. 2010 May 31;82(3-4):169-76
pubmed: 20385208
PLoS One. 2020 May 29;15(5):e0232785
pubmed: 32469871
Neuroimage. 2011 Jan;54 Suppl 1:S204-17
pubmed: 20550967
N Engl J Med. 1986 Aug 21;315(8):485-7
pubmed: 3736630
Ophthalmology. 2019 Apr;126(4):497-510
pubmed: 30114417
BMC Neurol. 2015 Feb 21;15:14
pubmed: 25886372
Acta Neuropathol. 2016 Dec;132(6):767-787
pubmed: 27645291
Invest Ophthalmol Vis Sci. 2015 Jun;56(6):3709-14
pubmed: 26047172
Alzheimers Dement. 2020 Mar 10;:
pubmed: 32157811
Curr Alzheimer Res. 2014 Mar;11(3):259-66
pubmed: 24484274
Alzheimers Dement (Amst). 2015 Apr 23;1(2):136-43
pubmed: 27239501
Doc Ophthalmol. 2010 Oct;121(2):111-21
pubmed: 20549299
Neurosci Lett. 2011 Mar 17;491(2):122-6
pubmed: 21236314
Ann Neurol. 1989 Aug;26(2):226-31
pubmed: 2774510
Eye (Lond). 2011 Mar;25(3):358-64
pubmed: 21212800
Acta Ophthalmol. 2016 Sep;94(6):e454-9
pubmed: 26895692
Ann Neurol. 2016 Jan;79(1):90-109
pubmed: 26505992
Invest Ophthalmol Vis Sci. 2017 May 1;58(6):BIO300-BIO306
pubmed: 29049835
Clin Exp Optom. 2017 Nov;100(6):668-675
pubmed: 28266057
Ann Neurol. 1989 Aug;26(2):221-5
pubmed: 2774509
Invest Ophthalmol Vis Sci. 2001 Feb;42(2):514-22
pubmed: 11157891
J Neural Transm Suppl. 1991;33:73-80
pubmed: 1753255
J Ophthalmic Vis Res. 2009 Apr;4(2):97-101
pubmed: 23198055
Ann N Y Acad Sci. 1991;640:44-6
pubmed: 1776758
Front Neurol. 2017 Dec 22;8:710
pubmed: 29312131
Front Cell Neurosci. 2013 Sep 19;7:142
pubmed: 24065883
Neurobiol Aging. 1996 May-Jun;17(3):377-84
pubmed: 8725899
Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8323-9
pubmed: 21917932
Neurology. 1984 Jul;34(7):939-44
pubmed: 6610841
Clin Neurophysiol. 2001 Oct;112(10):1860-7
pubmed: 11595144
Invest Ophthalmol Vis Sci. 1999 May;40(6):1124-36
pubmed: 10235545
Am J Ophthalmol. 1987 Aug 15;104(2):113-20
pubmed: 3618708
Ophthalmology. 2001 May;108(5):905-12
pubmed: 11320021
PLoS One. 2015 Aug 07;10(8):e0134750
pubmed: 26252902
Brain Res. 1989 Nov 6;501(2):364-72
pubmed: 2819446
Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1491-1500
pubmed: 30973577
Front Neurol. 2016 Apr 19;7:55
pubmed: 27148157
Ann Neurol. 1993 Mar;33(3):248-57
pubmed: 8498808
Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13892-7
pubmed: 26504198
J Neurol. 2014 Aug;261(8):1522-30
pubmed: 24846203
PLoS One. 2013 Nov 18;8(11):e79378
pubmed: 24260210
Surv Ophthalmol. 1989 Jul-Aug;34(1):31-43
pubmed: 2678551
Ophthalmic Surg Lasers Imaging Retina. 2015 Mar;46(3):310-4
pubmed: 25856815