Cationic Homopolymers Inhibit Spore and Vegetative Cell Growth of
Clostridioides difficile
Clostridium difficile
cationic
homopolymers
poly-β-peptides
therapeutics
Journal
ACS infectious diseases
ISSN: 2373-8227
Titre abrégé: ACS Infect Dis
Pays: United States
ID NLM: 101654580
Informations de publication
Date de publication:
14 05 2021
14 05 2021
Historique:
pubmed:
20
3
2021
medline:
24
6
2021
entrez:
19
3
2021
Statut:
ppublish
Résumé
A wide range of synthetic polymers have been explored for antimicrobial activity. These materials usually contain both cationic and hydrophobic subunits because these two characteristics are prominent among host-defense peptides. Here, we describe a series of nylon-3 polymers containing only cationic subunits and their evaluation against the gastrointestinal, spore-forming pathogen
Identifiants
pubmed: 33739823
doi: 10.1021/acsinfecdis.0c00843
pmc: PMC8130196
mid: NIHMS1695858
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1236-1247Subventions
Organisme : NIGMS NIH HHS
ID : T32 GM008169
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI106699
Pays : United States
Organisme : NIAID NIH HHS
ID : R33 AI121684
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008490
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI116933
Pays : United States
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