Evaluation of drug prescription pattern using World Health Organization prescribing indicators in public health facilities found in Ethiopia: systematic reviews and meta-analysis.
Drug use evaluation
Drug use patter
Literature review
Prescribing indicator
World Health Organization
Journal
Journal of pharmaceutical policy and practice
ISSN: 2052-3211
Titre abrégé: J Pharm Policy Pract
Pays: England
ID NLM: 101627192
Informations de publication
Date de publication:
19 Mar 2021
19 Mar 2021
Historique:
received:
27
11
2020
accepted:
09
03
2021
entrez:
20
3
2021
pubmed:
21
3
2021
medline:
21
3
2021
Statut:
epublish
Résumé
Drug use evaluation is a structured, methodological, and criteria-based drug assessment system that helps to evaluate the actual trend of drug use in a particular setting. If drug prescription practices are inappropriate, need to examine the patterns of drug use is necessary to change prescribing patterns accordingly. Therefore, this review aimed to determine the drug prescription pattern in public health facilities found in Ethiopia using prescribing indicators developed by the World Health Organization. This review was conducted as per the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline. Extensive searching to identify articles was conducted in PubMed, Medline, Web of Science, Research Gate, Africa Journal of Online, and Google scholar. Finally, 10 eligible articles were selected for analysis based on inclusion and exclusion criteria. The median value, as well as the 25th and 75th percentiles for each WHO prescribing indicator, were computed. The pooled median value of WHO prescribing indicators was reported as follows: the average number of drugs prescribed per encounter = 2.14 (IQR 1.79-2.52), the percentage of encounters with antibiotics prescribed = 43.46% (IQR 30.01-58.67), the percentage of encounters with an injection prescribed = 13.20% (6.47-40.7), percentage of drugs prescribed by generic name = 93.49% (89.13-97.96), and the percentage of medicines prescribed from essential medicines list = 92.54% (85.10-97.7). The forest plots determined for each prescribing indicator indicated that there is a high degree of heterogeneity across articles. All of the prescribing indicators were not consistent with the standard values recommended by the World Health Organization. Therefore, public health facilities should take appropriate measures for improving the prescription patterns as per the recommendation set by the World Health Organization.
Sections du résumé
BACKGROUND
BACKGROUND
Drug use evaluation is a structured, methodological, and criteria-based drug assessment system that helps to evaluate the actual trend of drug use in a particular setting. If drug prescription practices are inappropriate, need to examine the patterns of drug use is necessary to change prescribing patterns accordingly. Therefore, this review aimed to determine the drug prescription pattern in public health facilities found in Ethiopia using prescribing indicators developed by the World Health Organization.
METHODS
METHODS
This review was conducted as per the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline. Extensive searching to identify articles was conducted in PubMed, Medline, Web of Science, Research Gate, Africa Journal of Online, and Google scholar. Finally, 10 eligible articles were selected for analysis based on inclusion and exclusion criteria. The median value, as well as the 25th and 75th percentiles for each WHO prescribing indicator, were computed.
RESULT
RESULTS
The pooled median value of WHO prescribing indicators was reported as follows: the average number of drugs prescribed per encounter = 2.14 (IQR 1.79-2.52), the percentage of encounters with antibiotics prescribed = 43.46% (IQR 30.01-58.67), the percentage of encounters with an injection prescribed = 13.20% (6.47-40.7), percentage of drugs prescribed by generic name = 93.49% (89.13-97.96), and the percentage of medicines prescribed from essential medicines list = 92.54% (85.10-97.7). The forest plots determined for each prescribing indicator indicated that there is a high degree of heterogeneity across articles.
CONCLUSION
CONCLUSIONS
All of the prescribing indicators were not consistent with the standard values recommended by the World Health Organization. Therefore, public health facilities should take appropriate measures for improving the prescription patterns as per the recommendation set by the World Health Organization.
Identifiants
pubmed: 33741042
doi: 10.1186/s40545-021-00313-y
pii: 10.1186/s40545-021-00313-y
pmc: PMC7980606
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
31Références
Croat Med J. 2002 Aug;43(4):462-9
pubmed: 12187525
J Epidemiol Community Health. 1998 Jun;52(6):377-84
pubmed: 9764259
Popul Health Metr. 2017 Jul 21;15:29
pubmed: 28736507
PLoS Med. 2020 Jun 16;17(6):e1003139
pubmed: 32544153
Syst Rev. 2015 Jan 01;4:1
pubmed: 25554246
Arch Intern Med. 2006 Feb 13;166(3):332-7
pubmed: 16476874
BMC Health Serv Res. 2017 Feb 23;17(1):161
pubmed: 28231833
Drug Healthc Patient Saf. 2020 Jan 16;12:15-21
pubmed: 32021478
BMC Health Serv Res. 2013 May 07;13:170
pubmed: 23647871
BMC Public Health. 2016 Aug 22;16:724
pubmed: 27545670
J Clin Epidemiol. 2014 Aug;67(8):897-903
pubmed: 24794697
BMC Health Serv Res. 2016 Apr 23;16:144
pubmed: 27106610
Emerg Med Int. 2020 Feb 25;2020:4173586
pubmed: 32185081
Perspect Clin Res. 2015 Apr-Jun;6(2):86-90
pubmed: 25878953