Central nervous system infections associated with neurologic devices.


Journal

Current opinion in infectious diseases
ISSN: 1473-6527
Titre abrégé: Curr Opin Infect Dis
Pays: United States
ID NLM: 8809878

Informations de publication

Date de publication:
01 06 2021
Historique:
pubmed: 21 3 2021
medline: 26 8 2021
entrez: 20 3 2021
Statut: ppublish

Résumé

To review recent data on the epidemiology, microbiology, diagnosis, and management of central nervous system (CNS) infections associated with neurologic devices. The increasing use of implanted neurologic devices has led to an increase in associated infections. Cerebrospinal fluid (CSF) inflammation may be present after a neurosurgical procedure, complicating the diagnosis of CNS infection. Newer biomarkers such as CSF lactate and procalcitonin show promise in differentiating infection from other causes of CSF inflammation. Molecular diagnostic tests including next-generation or metagenomic sequencing may be superior to culture in identifying pathogens causing healthcare-associated ventriculitis and meningitis. Neurologic device infections are serious, often life-threatening complications. Rapid recognition and initiation of antibiotics are critical in decreasing morbidity. Device removal is usually required for cure.

Identifiants

pubmed: 33741795
doi: 10.1097/QCO.0000000000000723
pii: 00001432-202106000-00009
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

238-244

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Karen Bloch (K)

Department of Medicine (Infectious Diseases), Vanderbilt University Medical Center, Nashville, Tennessee.

Rodrigo Hasbun (R)

Section of Infectious Diseases, UT Health McGovern Medical School, Houston, Texas, USA.

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