Highly elevated levels, infant dietary exposure and health risks of medium-chain chlorinated paraffins in breast milk from China: Comparison with short-chain chlorinated paraffins.
Breast milk
Health risk
Medium-chain chlorinated paraffin
Short-chain chlorinated paraffin
Temporal trend
Journal
Environmental pollution (Barking, Essex : 1987)
ISSN: 1873-6424
Titre abrégé: Environ Pollut
Pays: England
ID NLM: 8804476
Informations de publication
Date de publication:
15 Jun 2021
15 Jun 2021
Historique:
received:
11
11
2020
revised:
14
01
2021
accepted:
04
03
2021
pubmed:
21
3
2021
medline:
4
5
2021
entrez:
20
3
2021
Statut:
ppublish
Résumé
Short-chain chlorinated paraffins (SCCPs) are persistent organic pollutants which are toxic to human. Median-chain chlorinated paraffins (MCCPs) have similar toxicity to SCCPs. The productions of chlorinated paraffins (CPs) in China were 1 million tons in 2013 and remained high after that, which may lead to high risks for human exposure to CPs. To investigate temporal trends and health risks of SCCPs and MCCPs in breast milk in China, samples (n = 2020) were collected from urban and rural areas of 11 Chinese provinces in 2017 and mixed into 42 pooled samples. SCCPs and MCCPs were analyzed by two-dimensional gas chromatography with electron-capture negative-ionization mass spectrometry (GC × GC-ECNI-MS). The MCCP concentrations (median (range)) were 472 (94-1714) and 567 (211-1089) ng g
Identifiants
pubmed: 33743436
pii: S0269-7491(21)00504-2
doi: 10.1016/j.envpol.2021.116922
pii:
doi:
Substances chimiques
Hydrocarbons, Chlorinated
0
Paraffin
8002-74-2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
116922Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.