Covid-19 and gender: lower rate but same mortality of severe disease in women-an observational study.
Aged
Aged, 80 and over
COVID-19
/ epidemiology
Comorbidity
Continuous Positive Airway Pressure
/ statistics & numerical data
Diabetes Mellitus
/ epidemiology
Female
Humans
Hypertension
/ epidemiology
Hypoxia
/ epidemiology
Italy
/ epidemiology
Kaplan-Meier Estimate
Male
Middle Aged
Myocardial Infarction
/ epidemiology
Noninvasive Ventilation
/ statistics & numerical data
SARS-CoV-2
Severity of Illness Index
Sex Factors
Smoking
/ epidemiology
Covid-19
Disease severity
Gender
Journal
BMC pulmonary medicine
ISSN: 1471-2466
Titre abrégé: BMC Pulm Med
Pays: England
ID NLM: 100968563
Informations de publication
Date de publication:
20 Mar 2021
20 Mar 2021
Historique:
received:
12
06
2020
accepted:
03
03
2021
entrez:
21
3
2021
pubmed:
22
3
2021
medline:
26
3
2021
Statut:
epublish
Résumé
Gender-related factors might affect vulnerability to Covid-19. The aim of this study was to describe the role of gender on clinical features and 28-day mortality in Covid-19 patients. Observational study of Covid-19 patients hospitalized in Bergamo, Italy, during the first three weeks of the outbreak. Medical records, clinical, radiological and laboratory findings upon admission and treatment have been collected. Primary outcome was 28-day mortality since hospitalization. 431 consecutive adult patients were admitted. Female patients were 119 (27.6%) with a mean age of 67.0 ± 14.5 years (vs 67.8 ± 12.5 for males, p = 0.54). Previous history of myocardial infarction, vasculopathy and former smoking habits were more common for males. At the time of admission PaO Hospitalized women are less likely to die from Covid-19; however, once severe disease occurs, the risk of dying is similar to men. Further studies are needed to better investigate the role of gender in clinical course and outcome of Covid-19.
Sections du résumé
BACKGROUND
BACKGROUND
Gender-related factors might affect vulnerability to Covid-19. The aim of this study was to describe the role of gender on clinical features and 28-day mortality in Covid-19 patients.
METHODS
METHODS
Observational study of Covid-19 patients hospitalized in Bergamo, Italy, during the first three weeks of the outbreak. Medical records, clinical, radiological and laboratory findings upon admission and treatment have been collected. Primary outcome was 28-day mortality since hospitalization.
RESULTS
RESULTS
431 consecutive adult patients were admitted. Female patients were 119 (27.6%) with a mean age of 67.0 ± 14.5 years (vs 67.8 ± 12.5 for males, p = 0.54). Previous history of myocardial infarction, vasculopathy and former smoking habits were more common for males. At the time of admission PaO
CONCLUSION
CONCLUSIONS
Hospitalized women are less likely to die from Covid-19; however, once severe disease occurs, the risk of dying is similar to men. Further studies are needed to better investigate the role of gender in clinical course and outcome of Covid-19.
Identifiants
pubmed: 33743654
doi: 10.1186/s12890-021-01455-0
pii: 10.1186/s12890-021-01455-0
pmc: PMC7980742
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
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