4-Methylumbelliferone Attenuates Macrophage Invasion and Myocardial Remodeling in Pressure-Overloaded Mouse Hearts.

Animals Flow Cytometry Heart / drug effects Hymecromone / pharmacology Hypertrophy, Left Ventricular / metabolism Macrophages / drug effects Male Mice Myocardium / metabolism Ventricular Remodeling / drug effects
extracellular matrix fibrosis hypertrophy inflammation macrophages pressure overload

Journal

Hypertension (Dallas, Tex. : 1979)
ISSN: 1524-4563
Titre abrégé: Hypertension
Pays: United States
ID NLM: 7906255

Informations de publication

Date de publication:
06 2021
Historique:
pubmed: 23 3 2021
medline: 13 1 2022
entrez: 22 3 2021
Statut: ppublish

Résumé

[Figure: see text].

Identifiants

DOI: 10.1161/HYPERTENSIONAHA.120.15247 PMID: 33745300
pubmed: 33745300
doi: 10.1161/HYPERTENSIONAHA.120.15247
doi:

Substances chimiques

Hymecromone 3T5NG4Q468

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1918-1927

Commentaires et corrections

Type : CommentIn

Auteurs

Katarzyna Hackert (K)

Susanne Homann (S)

From the Institute of Pharmacology and Clinical Pharmacology, and Cardiovascular Research Institute Düsseldorf (CARID), University Hospital Düsseldorf, Germany.

Shakila Mir (S)

From the Institute of Pharmacology and Clinical Pharmacology, and Cardiovascular Research Institute Düsseldorf (CARID), University Hospital Düsseldorf, Germany.

Arne Beran (A)

From the Institute of Pharmacology and Clinical Pharmacology, and Cardiovascular Research Institute Düsseldorf (CARID), University Hospital Düsseldorf, Germany.

Simone Gorreßen (S)

From the Institute of Pharmacology and Clinical Pharmacology, and Cardiovascular Research Institute Düsseldorf (CARID), University Hospital Düsseldorf, Germany.

Florian Funk (F)

From the Institute of Pharmacology and Clinical Pharmacology, and Cardiovascular Research Institute Düsseldorf (CARID), University Hospital Düsseldorf, Germany.

Jens W Fischer (JW)

From the Institute of Pharmacology and Clinical Pharmacology, and Cardiovascular Research Institute Düsseldorf (CARID), University Hospital Düsseldorf, Germany.

Maria Grandoch (M)

From the Institute of Pharmacology and Clinical Pharmacology, and Cardiovascular Research Institute Düsseldorf (CARID), University Hospital Düsseldorf, Germany.

Joachim P Schmitt (JP)

From the Institute of Pharmacology and Clinical Pharmacology, and Cardiovascular Research Institute Düsseldorf (CARID), University Hospital Düsseldorf, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › 4-Methylumbelliferone Attenuates Macrophage...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Cytophotométrie › Cytométrie en flux › 4-Methylumbelliferone Attenuates Macrophage...
questionsmedicales.fr › Système cardiovasculaire › Coeur › 4-Methylumbelliferone Attenuates Macrophage...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › Coumarines › Ombelliférones › Hymécromone › 4-Methylumbelliferone Attenuates Macrophage...
questionsmedicales.fr › États, signes et symptômes pathologiques › États anatomopathologiques › Hypertrophie › Cardiomégalie › Hypertrophie ventriculaire gauche › 4-Methylumbelliferone Attenuates Macrophage...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › 4-Methylumbelliferone Attenuates Macrophage...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › 4-Methylumbelliferone Attenuates Macrophage...
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Myocarde › 4-Methylumbelliferone Attenuates Macrophage...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Fonction ventriculaire › Remodelage ventriculaire › 4-Methylumbelliferone Attenuates Macrophage...